1-Methylhistidine

ChemistryAlso known as: 1-methyl-L-histidineAlso known as: N1-methylhistidineumol/L

Measures 1-methylhistidine levels in serum or plasma.

Normal Range

Consult your provider

umol/L

Abnormal Levels

Consult your provider

Specimen Type

Blood

Why This Biomarker Matters

Abnormal levels may indicate muscle breakdown or metabolic disorders affecting the nervous system, guiding diagnosis of rare conditions.

Overview

This test measures 1-methylhistidine, a modified amino acid, in serum or plasma. This amino acid is a product of muscle protein metabolism and dietary intake, particularly from meat. Elevated serum levels may indicate increased muscle protein turnover or dietary influences. It is used as a marker of dietary protein intake and muscle catabolism, and may be part of broader amino acid profiling panels for metabolic assessment.

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

1651-9Primary

1-Methylhistidine [Presence] in Serum or Plasma

26584-3

1-Methylhistidine [Moles/volume] in Cerebral spinal fluid

umol/L

1652-7

1-Methylhistidine [Mass/volume] in Serum or Plasma

mg/dL

25318-7

1-Methylhistidine [Moles/time] in 24 hour Urine

nmol/(24.h)

20633-4

1-Methylhistidine [Moles/volume] in Serum or Plasma

umol/L

27044-7

1-Methylhistidine [Moles/volume] in Urine

nmol/mL

27162-7

1-Methylhistidine [Moles/volume] in Amniotic fluid

umol/mL

50065-2

1-Methylhistidine [Moles/volume] in DBS

umol/L

50066-0

1-Methylhistidine [Moles/volume] in Body fluid

umol/L

6865-0

1-Methylhistidine [Mass/time] in 24 hour Urine

mg/(24.h)

13377-7

1-Methylhistidine [Mass/volume] in Cerebral spinal fluid

mg/dL

70179-7

1-Methylhistidine [Moles/volume] in Serum or Plasma from Fetus

umol/L

13406-4

1-Methylhistidine [Mass/volume] in Amniotic fluid

mg/dL

16302-2

1-Methylhistidine [Presence] in Urine

1653-5

1-Methylhistidine [Mass/volume] in Urine

mg/dL

25853-3

1-Methylhistidine [Moles/volume] in 24 hour Urine

nmol/L

Available Lab Tests

Order tests that measure this biomarker

Amino Acids (Plasma)

$193.00

Results in 3-7 business days