2-Hydroxy-3-Methylvalerate

2-Hydroxy-3-methylvalerate (2-HMV) is a compound detected in urine that indicates impaired branched-chain amino acid metabolism. Elevated levels suggest organic acidemia or other metabolic disorders affecting how the body processes certain amino acids. This test is often part of newborn screening or metabolic evaluation for unexplained symptoms like developmental delay, poor feeding, or metabolic crises. Early detection enables dietary management and medical intervention.