Cholinesterase^dibucaine/Cholinesterase

This test measures the activity of the enzyme butyrylcholinesterase (pseudocholinesterase) and its response to the drug dibucaine. It assesses genetic variants that affect how the body metabolizes certain anesthetic drugs, particularly succinylcholine and mivacurium. A low dibucaine number or absence of response indicates a genetic variation that impairs drug metabolism, putting individuals at risk for prolonged paralysis during anesthesia. This test is critical before surgery to identify those requiring modified anesthetic protocols.