Cotinine

ToxicologyAlso known as: Cotinine, urineAlso known as: Urine Cotinineug/mL

Measures cotinine, a metabolite of nicotine, indicating tobacco or nicotine product exposure.

Normal Range
0.013 ug/mL
ug/mL
Abnormal Levels
Consult your provider
Specimen Type
Blood

Why This Biomarker Matters

Cotinine levels objectively confirm tobacco exposure and monitor smoking cessation. This helps assess health risks from smoking or secondhand smoke and track quit attempts.

Understanding Your Results

Normal Range

0.013 ug/mL

Overview

Cotinine is a metabolite of nicotine produced when nicotine is broken down in your body. This test measures cotinine levels, which indicate tobacco or nicotine product use, including smoking, vaping, or exposure to secondhand smoke. Cotinine is detectable in blood, urine, and saliva for days to weeks after exposure. This test is used to assess tobacco exposure objectively, monitor smoking cessation efforts, and evaluate secondhand smoke exposure. It is valuable for clinical assessment, research, and occupational health screening.

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

59891-2Primary
Cotinine [Moles/volume] in Serum or Plasma
nmol/L
10366-3
Cotinine [Mass/volume] in Urine
ng/mL
12293-7
Cotinine [Presence] in Urine
9372-4
Cotinine [Mass/volume] in Specimen
ug/mL
35642-8
Cotinine [Presence] in Urine by Confirmatory method
61128-5
Cotinine [Presence] in Serum or Plasma
43196-5
Cotinine [Mass/volume] in Serum or Plasma by Confirmatory method
ng/mL
59645-2
Cotinine [Presence] in Serum or Plasma by Screen method
59646-0
Cotinine [Presence] in Urine by Screen method
74371-6
Cotinine [Mass/volume] in Saliva (oral fluid) by Confirmatory method
ng/mL
63044-2
Cotinine [Presence] in Saliva (oral fluid) by Screen method
10365-5
Cotinine [Mass/volume] in Serum or Plasma
ng/mL
59892-0
Cotinine [Moles/volume] in Gastric fluid
nmol/L
60299-5
Cotinine [Moles/volume] in Specimen
nmol/L
33796-4
Cotinine [Moles/volume] in Urine
nmol/L
40355-0
Cotinine [Presence] in Hair
72786-7
Cotinine [Mass/volume] in Urine by Screen method
ng/mL
74370-8
Cotinine [Presence] in Saliva (oral fluid) by Confirmatory method
10364-8
Cotinine [Mass/mass] in Hair
ng/g
92643-6
Cotinine [Mass/volume] in Urine by Confirmatory method
ng/mL
40418-6
Cotinine [Presence] in Meconium

Available Lab Tests

Order tests that measure this biomarker

Nicotine and Expanded Metabolites Urine Test

$56.85