Dodecanedioate/Creatinine

This test measures dodecanedioate (a 12-carbon dicarboxylic acid) relative to creatinine in urine, reflecting fatty acid oxidation metabolism. Elevated levels indicate abnormal breakdown of medium- and long-chain fatty acids. This pattern suggests possible metabolic disorders affecting energy production from fats. The ratio accounts for urine concentration variation. This test is typically ordered when metabolic disorders are suspected or as part of metabolic screening, particularly in infants or children with developmental concerns.