EPINEPHrine

ChemistryAlso known as: AdrenalineAlso known as: 1-(3,4-dihydroxyphenyl)-2-methylaminoethanolpg/mL

Measures epinephrine (adrenaline) metabolites in urine to assess adrenal hormone output.

Normal Range
0 – 110 pg/mL
pg/mL
Abnormal Levels
Consult your provider
Specimen Type
Blood

Why This Biomarker Matters

Abnormally high epinephrine can indicate pheochromocytoma or other adrenal disorders, which cause severe hypertension and cardiovascular complications. Identifying these enables appropriate treatment.

Understanding Your Results

Normal Range

0 – 110 pg/mL

Overview

This urine test measures epinephrine (adrenaline), a stress hormone produced by the adrenal glands. Epinephrine is released during 'fight or flight' responses, increasing heart rate and blood pressure. This test is primarily used to diagnose pheochromocytoma, a rare tumor of the adrenal glands that causes excessive epinephrine production, resulting in severe hypertension, sweating, and heart palpitations. Elevated urinary epinephrine warrants further investigation for adrenal disorders.

Research & Evidence

121 publications

Sort:
Efficacy and safety of intrathecal adjuvants for perioperative management of cesarean delivery: a systematic review and network meta-analysis of randomized controlled trials.
Reg Anesth Pain Med · 2025
PMID: 40147822Review
Pharmacokinetics and pharmacodynamics of AQST-109: Phase 3 results comparing epinephrine sublingual film with intramuscular injection.
Ann Allergy Asthma Immunol · 2025
PMID: 41297629Other
Sustainability of the de-implementation of low-value care in infants with bronchiolitis: 2-year follow-up of a cluster randomised controlled trial.
BMJ Qual Saf · 2025
PMID: 40651808Other
Pharmacokinetics and Pharmacodynamics Following Repeat Dosing of neffy (Epinephrine Nasal Spray) Versus Intramuscular Injection During Induced Allergic Rhinitis.
J Allergy Clin Immunol Pract · 2026
PMID: 41687867
Urinary Retention After Midurethral Sling: RCT of Retropubic Lidocaine Versus Saline.
Urogynecology (Phila) · 2026
PMID: 41627074
Effect of Combined Deep and Superficial Serratus Anterior Plane Block Versus Deep Serratus Anterior Plane Block on Postoperative Pain After Video-Assisted Thoracoscopic Surgery: A Prospective Randomized Trial.
J Cardiothorac Vasc Anesth · 2026
PMID: 41708366
[Comparative observation of analgesic efficacy between liposomal bupivacaine and "cocktail" therapy following artificial intelligence-assisted direct anterior approach total hip arthroplasty: A prospective randomized controlled study].
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi · 2026
PMID: 41981425
Novel Epinephrine Delivery Devices.
Immunol Allergy Clin North Am · 2026
PMID: 41932751
Disrupted neurovascular-endocrine coupling in type 1 diabetes with impaired awareness of hypoglycemia.
J Clin Invest · 2026
PMID: 41712301
Neffy: A latest needle-free epinephrine.
Saudi J Anaesth · 2026
PMID: 42022066

Research data from MEDLINE/PubMed · 121 articles

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

11046-0Primary
EPINEPHrine [Mass/volume] in Urine
pg/mL
32015-0
EPINEPHrine [Mass/volume] in 24 hour Urine
ng/L
2230-1
EPINEPHrine [Mass/volume] in Plasma
pg/mL
2232-7
EPINEPHrine [Mass/time] in 24 hour Urine
ug/(24.h)
14712-4
EPINEPHrine [Moles/time] in 24 hour Urine
nmol/(24.h)
24521-7
EPINEPHrine [Moles/volume] in Urine
nmol/L
25908-5
EPINEPHrine [Moles/volume] in 24 hour Urine
nmol/L
14711-6
EPINEPHrine [Moles/volume] in Plasma
nmol/L

Available Lab Tests

Order tests that measure this biomarker

Catecholamines, Fractionated (24-Hour Urine with C)

$271.21
Results in 3-5 business days

Catecholamines, Fractionated (Plasma)

$136.71
Results in 3-5 business days

catecholamines fractionated random urine test

$88.00