Interleukin 6

ChemistryAlso known as: Il6 CSF-mCncAlso known as: Il6 Fld-mCncAlso known as: Il6 Msmt SerPlpg/mL

Measures a protein (cytokine) produced during inflammatory immune responses.

Normal Range
3 – 5
pg/mL
Abnormal Levels
< 0 pg/mL
> 5 pg/mL
Specimen Type
Blood

Why This Biomarker Matters

IL-6 is a marker of systemic inflammation linked to infection, autoimmune disease, and cardiovascular risk. Elevated levels guide anti-inflammatory treatment decisions.

Optimal Ranges

Clinician-defined 4-point reference thresholds (pg/mL)

Default Range

0
3
4
5
Low
0 pg/mL
Borderline Low
3 pg/mL
Optimal
4 pg/mL
Borderline High
5 pg/mL

Overview

Interleukin 6 (IL-6) is a signaling protein (cytokine) produced by immune cells and tissues in response to inflammation or infection. Elevated IL-6 levels indicate systemic inflammation and are associated with various conditions including infections, rheumatoid arthritis, cardiovascular disease, and cancer. IL-6 is also elevated during acute stress and can indicate recovery status after surgery or illness. Measuring IL-6 helps assess inflammation severity and monitor treatment response in inflammatory conditions.

Research & Evidence

100 publications

Sort:

Research data from MEDLINE/PubMed · 100 articles

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

26881-3Primary
Interleukin 6 [Mass/volume] in Serum or Plasma
pg/mL
44322-6
Interleukin 6 [Presence] in Serum or Plasma
49732-1
Interleukin 6 [Mass/volume] in Body fluid
pg/mL
49919-4
Interleukin 6 [Mass/volume] in Cerebral spinal fluid
pg/mL

Available Lab Tests

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