Prealbumin

Prealbumin, also called transthyretin, is a protein synthesized by the liver that transports thyroxine and retinol-binding protein. It has a short half-life (2-3 days), making it a sensitive marker of recent nutritional status and liver synthetic function. Low prealbumin levels indicate protein malnutrition, inadequate caloric intake, or liver disease. High levels are less common but can occur in kidney disease or dehydration. Prealbumin is particularly useful for monitoring nutritional interventions and recovery in hospitalized patients.