Tissue transglutaminase Ab panel

Tissue transglutaminase (tTG) antibodies are markers of celiac disease, an autoimmune disorder triggered by gluten consumption. When people with celiac disease eat gluten (found in wheat, barley, and rye), their immune system produces antibodies against tTG, damaging the small intestine. This antibody panel test typically includes IgA anti-tTG and/or IgG anti-tTG. A positive result suggests celiac disease and should be confirmed with intestinal biopsy. This test is essential for diagnosing celiac disease before it causes complications like nutritional deficiencies, osteoporosis, or increased cancer risk.