Valine

ChemistryAlso known as: L-ValineAlso known as: 2-Amino-3-methylbutanoic acidAlso known as: Valmg/dL

Measures the level of valine, an essential amino acid, in serum or plasma.

Normal Range
Consult your provider
mg/dL
Abnormal Levels
Consult your provider
Specimen Type
Blood

Why This Biomarker Matters

Abnormal valine levels can signal inherited metabolic disorders that, if caught early, can be managed to prevent serious neurological damage.

Overview

Valine is an essential amino acid your body cannot produce and must obtain from foods like meat, dairy, nuts, and legumes. This urine test measures valine levels and is typically used in genetic metabolic screening, particularly for amino acid metabolism disorders. Abnormal urine valine levels can indicate conditions like maple syrup urine disease (MSUD) or other inherited metabolic disorders affecting amino acid processing. Early detection through newborn screening or in symptomatic individuals is critical, as these conditions can cause serious neurological problems if untreated.

Research & Evidence

82 publications

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Genetically encoded FRET sensor for fructosyl valine detection in living cells.
Spectrochim Acta A Mol Biomol Spectrosc · 2026
PMID: 41980557

Research data from MEDLINE/PubMed · 82 articles

Technical Information (LOINC Codes)

Standardized laboratory codes for this biomarker

20661-5Primary
Valine [Moles/volume] in Serum or Plasma
umol/L
3119-5
Valine [Mass/volume] in Urine
mg/dL
26961-3
Valine [Moles/volume] in Urine
nmol/mL
47799-2
Valine [Moles/volume] in DBS
umol/L
9623-0
Valine [Presence] in Urine
3118-7
Valine [Mass/volume] in Serum or Plasma
mg/dL
3120-3
Valine [Mass/time] in 24 hour Urine
mg/(24.h)
25553-9
Valine [Moles/time] in 24 hour Urine
umol/(24.h)
22649-8
Valine [Moles/volume] in Cerebral spinal fluid
umol/L
3117-9
Valine [Presence] in Serum or Plasma
13419-7
Valine [Mass/volume] in Amniotic fluid
mg/dL
3116-1
Valine [Mass/volume] in Cerebral spinal fluid
mg/dL
26873-0
Valine [Moles/volume] in Amniotic fluid
umol/dL
32278-4
Valine [Moles/volume] in Vitreous fluid
umol/L
32279-2
Valine [Moles/volume] in Body fluid
umol/L
41169-4
Valine [Presence] in Blood
26001-8
Valine [Moles/volume] in 24 hour Urine
umol/L
22729-8
Valine [Moles/volume] in Specimen
umol/L

Available Lab Tests

Order tests that measure this biomarker

Valine: Normal Range, Testing & Clinical Significance | Healos | Healos