Overview
Alexander disease type II is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormal medulla oblongata morphology
Very frequent (80-99%)HP:0011441
Cervical spinal cord atrophy
Very frequent (80-99%)HP:0010873
Abnormality of the periventricular white matter
Frequent (30-79%)HP:0002518
Ataxia
Frequent (30-79%)HP:0001251
Autonomic dysregulation
Frequent (30-79%)HP:0012332
Deglutition disorder
Frequent (30-79%)HP:0002015
Difficulty articulating speech
Frequent (30-79%)HP:0001260
Dysphonia
Frequent (30-79%)HP:0001618
Extensor plantar responses
Frequent (30-79%)HP:0003487
Increased reflexes
Frequent (30-79%)HP:0001347
Involuntary muscle stiffness, contraction, or spasm
Frequent (30-79%)HP:0001257
Involuntary, rapid, rhythmic eye movements
Frequent (30-79%)HP:0000639
Limb muscle weakness
Frequent (30-79%)HP:0003690
Palatal tremor
Frequent (30-79%)HP:0010530
Periventricular cysts
Frequent (30-79%)HP:0007109
Spastic paraparesis
Frequent (30-79%)HP:0002313
Sphincter disturbances
Frequent (30-79%)HP:0002839
Cobb angle greater than ten degrees
Occasional (5-29%)HP:0002650
Muscle rigidity
Occasional (5-29%)HP:0002063
Trouble sleeping
Occasional (5-29%)HP:0002360
Related Conditions
Quick Facts
- SNOMED CT
- 1332388003
- UMLS CUI
- C5679914
- Fully Specified Name
- Alexander disease type II (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 20
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.