Autosomal dominant spastic paraplegia type 37

disorder

SNOMED 763369007CUI C2936880

Overview

Autosomal dominant spastic paraplegia type 37 is a disorder.

Auto-generated from clinical reference data. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Degeneration of the lateral corticospinal tracts

Very frequent (80-99%)HP:0002314

Progressive spastic paraplegia

Very frequent (80-99%)HP:0007020

Distal sensory loss, especially vibratory sense

Frequent (30-79%)HP:0002166

Extensor plantar responses

Frequent (30-79%)HP:0003487

Increased reflexes

Frequent (30-79%)HP:0001347

Lower limb muscle weakness

Frequent (30-79%)HP:0007340

Spasticity of lower limb

Frequent (30-79%)HP:0002061

Spinal cord lesion

Frequent (30-79%)HP:0100561

Ankle clonus

Occasional (5-29%)HP:0011448

Clonus

Occasional (5-29%)HP:0002169

Gait disturbance

Occasional (5-29%)HP:0001288

Muscle spasm

Occasional (5-29%)HP:0003394

Pes cavus

Occasional (5-29%)HP:0001761

Tiredness

Occasional (5-29%)HP:0012378

Upper extremity spasticity

Occasional (5-29%)HP:0006986

Upper limb hyperreflexia

Occasional (5-29%)HP:0007350

Lower limb hyperreflexia

HP:0002395

Overactive bladder

HP:0000012

Spastic paraplegia

HP:0001258

Spastic walk

HP:0002064

Urinary incontinence

HP:0000020

Related Conditions

Pure hereditary spastic paraplegia(parent)

Autosomal dominant hereditary spastic paraplegia(parent)

Quick Facts

SNOMED CT: 763369007
UMLS CUI: C2936880
Fully Specified Name: Autosomal dominant spastic paraplegia type 37 (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 21

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.