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Autosomal dominant spastic paraplegia type 42
disorderSNOMED 763070001CUI C2675528
Overview
Autosomal dominant spastic paraplegia type 42 is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Degeneration of the lateral corticospinal tracts
Very frequent (80-99%)HP:0002314
Extensor plantar responses
Very frequent (80-99%)HP:0003487
Increased reflexes
Very frequent (80-99%)HP:0001347
Lower limb hypertonia
Very frequent (80-99%)HP:0006895
Progressive spastic paraplegia
Very frequent (80-99%)HP:0007020
Spastic walk
Very frequent (80-99%)HP:0002064
Spasticity of lower limb
Very frequent (80-99%)HP:0002061
Clonus
Frequent (30-79%)HP:0002169
Distal sensory loss, especially vibratory sense
Frequent (30-79%)HP:0002166
Lower limb amyotrophy
Frequent (30-79%)HP:0007210
Lower limb muscle weakness
Frequent (30-79%)HP:0007340
Spinal cord lesion
Frequent (30-79%)HP:0100561
Cavus foot
Occasional (5-29%)HP:0001761
Lower limb hyperreflexia
HP:0002395
Muscle degeneration
HP:0003202
Muscle weakness
HP:0001324
Spastic paraplegia
HP:0001258
Quick Facts
- SNOMED CT
- 763070001
- UMLS CUI
- C2675528
- Fully Specified Name
- Autosomal dominant spastic paraplegia type 42 (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 17
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.