Specialists & Providers
Diagnostic Biomarkers
Diagnostic & Clinical Standards
Authoritative clinical thresholds and screening guidelines from major medical bodies.
CKD Definition
KDIGO2024
Chronic kidney disease (CKD) is defined as abnormalities of kidney structure or function that have been present for 3 months or more. This can include reduced kidney filtration (GFR below 60) or markers of kidney damage such as elevated protein in the urine.
CKD GFR Staging
KDIGO2024
Kidney function is classified into categories based on glomerular filtration rate (GFR), a measure of how well the kidneys filter waste. Categories range from G1 (normal or high, GFR 90 or above) to G5 (kidney failure, GFR below 15).
Kidney filtration rate is normal or high. GFR alone does not indicate CKD at this level; additional markers of kidney damage are needed.
Kidney filtration rate is mildly decreased. As with G1, additional markers of kidney damage are needed for CKD diagnosis.
Kidney filtration rate is mildly to moderately decreased. CKD is diagnosed at this level with or without other markers of damage.
Kidney filtration rate is moderately to severely decreased. Nephrology referral is generally recommended.
Kidney filtration rate is severely decreased. Preparation for kidney replacement therapy may be appropriate.
Kidney filtration rate is at or near kidney failure. Dialysis or kidney transplant may be needed.
CKD Albuminuria Staging
KDIGO2024
Albuminuria (protein in urine) is classified into three categories: A1 (normal to mildly increased, less than 30 mg/g), A2 (moderately increased, 30-300 mg/g), and A3 (severely increased, more than 300 mg/g). Higher levels indicate greater kidney damage.
Urine albumin levels are within the normal or mildly increased range.
Urine albumin levels are moderately increased (previously termed microalbuminuria). Indicates kidney damage and increased cardiovascular risk.
Urine albumin levels are severely increased (previously termed macroalbuminuria). Indicates significant kidney damage.
CKD CGA Staging
KDIGO2024
CKD is classified using a three-part system: Cause (what is causing the kidney disease), GFR category (G1-G5, how well the kidneys filter), and Albuminuria category (A1-A3, how much protein is in the urine). This CGA system provides a complete picture of kidney disease severity and prognosis.
Related Conditions
Quick Facts
- SNOMED CT
- 709044004
- UMLS CUI
- C0403447
- Fully Specified Name
- Chronic kidney disease (disorder)
- Specialists
- 2
- Diagnostic Biomarkers
- 3
Related Health Goals
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.