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Chronic kidney disease

disorder
SNOMED 709044004CUI C0403447

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Diagnostic & Clinical Standards

Authoritative clinical thresholds and screening guidelines from major medical bodies.

CKD Definition

KDIGO2024

Chronic kidney disease (CKD) is defined as abnormalities of kidney structure or function that have been present for 3 months or more. This can include reduced kidney filtration (GFR below 60) or markers of kidney damage such as elevated protein in the urine.

CKD GFR Staging

KDIGO2024

Kidney function is classified into categories based on glomerular filtration rate (GFR), a measure of how well the kidneys filter waste. Categories range from G1 (normal or high, GFR 90 or above) to G5 (kidney failure, GFR below 15).

G1 — Normal or High≥ 90mL/min/1.73m²

Kidney filtration rate is normal or high. GFR alone does not indicate CKD at this level; additional markers of kidney damage are needed.

G2 — Mildly Decreased60 – 89mL/min/1.73m²

Kidney filtration rate is mildly decreased. As with G1, additional markers of kidney damage are needed for CKD diagnosis.

G3a — Mildly to Moderately Decreased45 – 59mL/min/1.73m²

Kidney filtration rate is mildly to moderately decreased. CKD is diagnosed at this level with or without other markers of damage.

G3b — Moderately to Severely Decreased30 – 44mL/min/1.73m²

Kidney filtration rate is moderately to severely decreased. Nephrology referral is generally recommended.

G4 — Severely Decreased15 – 29mL/min/1.73m²

Kidney filtration rate is severely decreased. Preparation for kidney replacement therapy may be appropriate.

G5 — Kidney Failure< 15mL/min/1.73m²

Kidney filtration rate is at or near kidney failure. Dialysis or kidney transplant may be needed.

CKD Albuminuria Staging

KDIGO2024

Albuminuria (protein in urine) is classified into three categories: A1 (normal to mildly increased, less than 30 mg/g), A2 (moderately increased, 30-300 mg/g), and A3 (severely increased, more than 300 mg/g). Higher levels indicate greater kidney damage.

A1 — Normal to Mildly Increased< 30mg/g

Urine albumin levels are within the normal or mildly increased range.

A2 — Moderately Increased30 – 300mg/g

Urine albumin levels are moderately increased (previously termed microalbuminuria). Indicates kidney damage and increased cardiovascular risk.

A3 — Severely Increased> 300mg/g

Urine albumin levels are severely increased (previously termed macroalbuminuria). Indicates significant kidney damage.

CKD CGA Staging

KDIGO2024

CKD is classified using a three-part system: Cause (what is causing the kidney disease), GFR category (G1-G5, how well the kidneys filter), and Albuminuria category (A1-A3, how much protein is in the urine). This CGA system provides a complete picture of kidney disease severity and prognosis.

Quick Facts

SNOMED CT
709044004
UMLS CUI
C0403447
Fully Specified Name
Chronic kidney disease (disorder)
Specialists
2
Diagnostic Biomarkers
3

Related Health Goals

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.