Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormality of tooth eruption
Very frequent (80-99%)HP:0006292
Cleft lip, cleft palate
Frequent (30-79%)HP:0000202
Cleft of palate
Frequent (30-79%)HP:0000175
Delayed language development
Frequent (30-79%)HP:0000750
Feeding difficulties in infancy
Frequent (30-79%)HP:0008872
Oral pharyngeal dysphagia
Frequent (30-79%)HP:0200136
Poor sucking
Frequent (30-79%)HP:0002033
Recurrent middle ear infection
Frequent (30-79%)HP:0000403
Speech articulation difficulties
Frequent (30-79%)HP:0009088
Unilateral palatoschisis
Frequent (30-79%)HP:0100334
Velopharyngeal dysfunction
Frequent (30-79%)HP:0000220
Abnormal permanent tooth count
Occasional (5-29%)HP:0011044
Angle class 3 malocclusion
Occasional (5-29%)HP:0000689
Failure of development of lateral incisor
Occasional (5-29%)HP:0200153
Hearing loss, conductive
Occasional (5-29%)HP:0000405
Hole in roof of mouth
Occasional (5-29%)HP:0010294
Malnutrition
Occasional (5-29%)HP:0004395
Nasal speech
Occasional (5-29%)HP:0001611
Peg-shaped maxillary lateral incisors
Occasional (5-29%)HP:0006342
Right and left cleft palate
Occasional (5-29%)HP:0100337
Hypotrophic maxilla
Very rare (1-4%)HP:0000327
Related Conditions
Cleft upper lip, upper jaw AND palate(child)
Cheilognathouranoschisis(child)
Central complete cleft palate with cleft lip(child)
Central incomplete cleft palate with cleft lip(child)
Cleft of soft palate and cleft lip(child)
Cleft of hard palate and cleft lip(child)
Cleft lip and cleft palate with ectodermal dysplasia syndrome(child)
Lowry Yong syndrome(child)
Uveal coloboma with cleft lip and palate and intellectual disability syndrome(child)
McPherson Clemens syndrome(child)
Cholestasis with pigmentary retinopathy and cleft palate syndrome(child)
Hypertelorism with microtia and facial clefting syndrome(child)
XY type gonadal dysgenesis with associated anomalies syndrome(child)
Cleft palate with left cleft lip(child)
Cleft palate with right cleft lip(child)
Pilotto syndrome(child)
Holzgreve Wagner Rehder syndrome(child)
Cleft lip and palate, craniofacial dysmorphism, congenital heart defect, hearing loss syndrome(child)
Dysraphism, cleft lip and palate, limb reduction defect syndrome(child)
Cleft palate(parent)
Quick Facts
- SNOMED CT
- 66948001
- UMLS CUI
- C0158646
- Fully Specified Name
- Cleft palate with cleft lip (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 21
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.