Research Evidence
Peer-reviewed studies linked via MeSH term "Syphilis, Congenital" from the MEDLINE/PubMed database.
Sort:
Reinfection caused by gestational syphilis: A case report and systematic review of the literature
[object Object], [object Object], [object Object] et al. · Rev Colomb Obstet Ginecol · 2025
Health care of sexual partners of adolescents with gestational syphilis and their children: an integrative review.
[object Object], [object Object], [object Object] et al. · Cien Saude Colet · 2024
PMID: 38747774Meta-Analysis
Syphilis management in pregnancy: a review of guideline recommendations from countries around the world.
[object Object], [object Object], [object Object] et al. · Sex Reprod Health Matters · 2019
Antibiotic treatment for newborns with congenital syphilis.
[object Object], [object Object], [object Object] et al. · Cochrane Database Syst Rev · 2019
Screening for Syphilis Infection in Pregnant Women: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
[object Object], [object Object], [object Object] · JAMA · 2018
PMID: 30193282Meta-Analysis
A systematic review and meta-analysis of studies evaluating the performance and operational characteristics of dual point-of-care tests for HIV and syphilis.
[object Object], [object Object], [object Object] et al. · Sex Transm Infect · 2017
The Global Epidemiology of Syphilis in the Past Century - A Systematic Review Based on Antenatal Syphilis Prevalence.
[object Object], [object Object], [object Object] · PLoS Negl Trop Dis · 2016
Gestational syphilis and stillbirth in the Americas: a systematic review and meta-analysis.
[object Object], [object Object], [object Object] · Rev Panam Salud Publica · 2015
PMID: 26245178Meta-Analysis
Strategies of testing for syphilis during pregnancy.
[object Object], [object Object], [object Object] et al. · Cochrane Database Syst Rev · 2014
Safety of benzathine penicillin for preventing congenital syphilis: a systematic review.
[object Object], [object Object], [object Object] et al. · PLoS One · 2013
Search all PubMed articles for Congenital syphilis
Research data from MEDLINE/PubMed
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Blood spots
Frequent (30-79%)HP:0000979
Extramedullary hematopoiesis
Frequent (30-79%)HP:0001978
Hepatosplenomegaly
Frequent (30-79%)HP:0001433
Hydrops fetalis
Frequent (30-79%)HP:0001789
Large placenta
Frequent (30-79%)HP:0006267
Low platelet count
Frequent (30-79%)HP:0001873
Maculopapular exanthema
Frequent (30-79%)HP:0040186
Osteochondrosis
Frequent (30-79%)HP:0040188
Periostalgia
Frequent (30-79%)HP:0040165
Petechiae
Frequent (30-79%)HP:0000967
Premature birth
Frequent (30-79%)HP:0001622
Cataract
Occasional (5-29%)HP:0000518
Cerebrospinal fluid pleocytosis
Occasional (5-29%)HP:0012229
Chorioretinitis
Occasional (5-29%)HP:0012424
Corneal inflammation
Occasional (5-29%)HP:0000491
Diarrhea
Occasional (5-29%)HP:0002014
Frontal protuberance
Occasional (5-29%)HP:0002007
Glaucoma
Occasional (5-29%)HP:0000501
High arched palate
Occasional (5-29%)HP:0000218
Hutchinson incisor
Occasional (5-29%)HP:0033782
Hypertrophy of maxilla
Occasional (5-29%)HP:0430028
Hypoacusis
Occasional (5-29%)HP:0000365
Inflammation of heart muscle
Occasional (5-29%)HP:0012819
Intestinal malabsorption
Occasional (5-29%)HP:0002024
Low number of red blood cells or hemoglobin
Occasional (5-29%)HP:0001903
Nephrosis
Occasional (5-29%)HP:0000100
Neurodevelopmental delay
Occasional (5-29%)HP:0012758
Notched primary central incisor
Occasional (5-29%)HP:0012413
Palmoplantar scaling skin
Occasional (5-29%)HP:0025524
Pancreatitis
Occasional (5-29%)HP:0001733
Related Conditions
Congenital syphilitic periostitis(child)
Early congenital syphilis (less than 2 years)(child)
Juvenile syphilis(child)
Hutchinson's teeth(child)
Congenital syphilis with gumma(child)
Congenital syphilitic choroiditis(child)
Moon's molar teeth(child)
Congenital syphilitic hepatomegaly(child)
Late congenital neurosyphilis(child)
Mulberry molar teeth(child)
Syphilis(parent)
Congenital bacterial disorder(parent)
Quick Facts
- SNOMED CT
- 35742006
- UMLS CUI
- C0039131
- Fully Specified Name
- Congenital syphilis (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.