Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormality of the fingernails
Very frequent (80-99%)HP:0001231
Acanthosis nigricans
Very frequent (80-99%)HP:0000956
Concave nail
Very frequent (80-99%)HP:0001598
Decreased body height
Very frequent (80-99%)HP:0004322
Deep-set nails
Very frequent (80-99%)HP:0001814
Delayed skeletal development
Very frequent (80-99%)HP:0002750
Dermatopathy
Very frequent (80-99%)HP:0000951
Epidermal hyperkeratosis
Very frequent (80-99%)HP:0000962
Eyelid ptosis
Very frequent (80-99%)HP:0000508
Failure to thrive in first year of life
Very frequent (80-99%)HP:0001531
Feeding difficulties in infancy
Very frequent (80-99%)HP:0008872
Flat nasal bridge
Very frequent (80-99%)HP:0005280
Lack of skin elasticity
Very frequent (80-99%)HP:0100679
Large head
Very frequent (80-99%)HP:0000256
Loose redundant skin
Very frequent (80-99%)HP:0001582
Narrow palate
Very frequent (80-99%)HP:0000189
Pulmonary stenosis
Very frequent (80-99%)HP:0001642
Short neck
Very frequent (80-99%)HP:0000470
VSD
Very frequent (80-99%)HP:0001629
Wooly hair
Very frequent (80-99%)HP:0002224
Abnormal curving of the cornea or lens of the eye
Frequent (30-79%)HP:0000483
Abnormal dermatoglyphics
Frequent (30-79%)HP:0007477
Cardiomyopathy, hypertrophic
Frequent (30-79%)HP:0001639
Cerebral cortex atrophy
Frequent (30-79%)HP:0002120
Cryptorchidism
Frequent (30-79%)HP:0000028
Dental anomalies
Frequent (30-79%)HP:0000164
Dull intelligence
Frequent (30-79%)HP:0001249
Dystrophic tooth enamel
Frequent (30-79%)HP:0000682
Gastroesophageal reflux disease
Frequent (30-79%)HP:0002020
Hydramnios
Frequent (30-79%)HP:0001561
Related Conditions
Quick Facts
- SNOMED CT
- 309776008
- UMLS CUI
- C0587248
- Fully Specified Name
- Costello syndrome (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.