Research Evidence
Peer-reviewed studies linked via MeSH term "Felty Syndrome" from the MEDLINE/PubMed database.
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Aleukemic variant of T-cell large granular lymphocyte leukemia in patients with rheumatoid arthritis - diagnostically challenging subtype.
[object Object], [object Object] · Expert Rev Clin Immunol · 2024
PMID: 39049194Review
The spectrum of somatic mutations in large granular lymphocyte leukemia, rheumatoid arthritis, and Felty's syndrome.
[object Object], [object Object], [object Object] · Semin Hematol · 2022
PMID: 36115688Review
Hematological Manifestations among Patients with Rheumatic Diseases.
[object Object], [object Object] · Acta Haematol · 2021
PMID: 33221805Review
Chronic neutropenia in LGL leukemia and rheumatoid arthritis.
[object Object], [object Object] · Hematology Am Soc Hematol Educ Program · 2017
Treatment of pseudo Felty's syndrome: Is there a place for rituximab?
[object Object], [object Object], [object Object] et al. · Joint Bone Spine · 2015
PMID: 25623522Review
Citrullination of autoantigens implicates NETosis in the induction of autoimmunity.
[object Object], [object Object] · Ann Rheum Dis · 2014
PMID: 24291655Review
[Large granular lymphocyte leukemia: clinical and pathogenic aspects].
[object Object], [object Object], [object Object] et al. · Rev Med Interne · 2013
PMID: 23928096Review
Autoimmune manifestations in large granular lymphocyte leukemia.
[object Object], [object Object] · Clin Lymphoma Myeloma Leuk · 2012
PMID: 22999943Review
Neutrophil activation and B-cell stimulation in the pathogenesis of Felty's syndrome.
[object Object], [object Object] · Pol Arch Med Wewn · 2012
PMID: 22814518Review
Gastrointestinal and hepatic manifestations of rheumatoid arthritis.
[object Object], [object Object] · Dig Dis Sci · 2011
PMID: 21203902Review
Search all PubMed articles for Felty's syndrome
Research data from MEDLINE/PubMed
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Arthralgias
Very frequent (80-99%)HP:0002829
Arthritis
Very frequent (80-99%)HP:0001369
Autoimmunity
Very frequent (80-99%)HP:0002960
Breakdown of bone
Very frequent (80-99%)HP:0002797
Immune deficiency
Very frequent (80-99%)HP:0002721
Joint disease
Very frequent (80-99%)HP:0001367
Limitation of joint mobility
Very frequent (80-99%)HP:0001376
Multiple, subcutaneous nodules
Very frequent (80-99%)HP:0001482
Neutropoenia
Very frequent (80-99%)HP:0001875
Predisposition to infections
Very frequent (80-99%)HP:0002719
respiratory infections, recurrent
Very frequent (80-99%)HP:0002205
Synovitis
Very frequent (80-99%)HP:0100769
Abnormal lymphocytes
Frequent (30-79%)HP:0004332
Chronic middle ear infection
Frequent (30-79%)HP:0000389
Decreased haemoglobin
Frequent (30-79%)HP:0001903
Large spleen
Frequent (30-79%)HP:0001744
Lymph node hyperplasia
Frequent (30-79%)HP:0002716
Nasal inflammation
Frequent (30-79%)HP:0012384
Pneumonia, recurrent
Frequent (30-79%)HP:0006532
Recurrent sore throat
Frequent (30-79%)HP:0100776
Sinusitis
Frequent (30-79%)HP:0000246
Weight loss
Frequent (30-79%)HP:0001824
Bacterial infection of skin
Occasional (5-29%)HP:0100658
Cancer of lymphatic system
Occasional (5-29%)HP:0002665
Enlarged liver
Occasional (5-29%)HP:0002240
Episcleritis
Occasional (5-29%)HP:0100534
Generalised hyperpigmentation
Occasional (5-29%)HP:0007440
Hypoplastic bone marrow
Occasional (5-29%)HP:0005528
Infection in blood stream
Occasional (5-29%)HP:0100806
Irregular hyperpigmentation
Occasional (5-29%)HP:0007400
Quick Facts
- SNOMED CT
- 57160007
- UMLS CUI
- C0015773
- Fully Specified Name
- Felty's syndrome (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.