Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Cognitive deficits
Very frequent (80-99%)HP:0100543
Dysesthesia
Very frequent (80-99%)HP:0012534
Inability to coordinate movements when walking
Very frequent (80-99%)HP:0002066
Lower limb muscle weakness
Very frequent (80-99%)HP:0007340
Abnormal central sensory function
Frequent (30-79%)HP:0011730
Abnormal pyramidal tract morphology
Frequent (30-79%)HP:0002062
Absent deep tendon reflexes
Frequent (30-79%)HP:0001284
Acroparesthesia
Frequent (30-79%)HP:0031006
Brain imaging abnormality
Frequent (30-79%)HP:0410263
Cerebellar abnormality
Frequent (30-79%)HP:0001317
Difficulty articulating speech
Frequent (30-79%)HP:0001260
Extrapyramidal syndrome
Frequent (30-79%)HP:0002071
Intellectual deterioration
Frequent (30-79%)HP:0001268
Paresthesia
Frequent (30-79%)HP:0003401
Reduced tendon reflexes
Frequent (30-79%)HP:0001315
Trouble sleeping
Frequent (30-79%)HP:0002360
Myoclonus of limbs
Occasional (5-29%)HP:0045084
Aggression
HP:0000718
Appendicular ataxia
HP:0002070
Apraxia
HP:0002186
Degeneration of cerebellum
HP:0001272
Depressive episode
HP:0000716
Emotional lability
HP:0000712
Impaired smooth pursuit
HP:0007772
Increased reflexes
HP:0001347
Instability or lack of coordination of central trunk muscles
HP:0002078
Involuntary muscle stiffness, contraction, or spasm
HP:0001257
Jerking
HP:0001336
Memory impairment
HP:0002354
Muscle rigidity
HP:0002063
Quick Facts
- SNOMED CT
- 67155006
- UMLS CUI
- C0017495
- Fully Specified Name
- Gerstmann-Straussler-Scheinker syndrome (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.