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Hereditary factor V deficiency disease

disorder
SNOMED 88776002CUI C0015499

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Research Evidence

Peer-reviewed studies linked via MeSH term "Factor V Deficiencies" from the MEDLINE/PubMed database.

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Thrombophilic disorders and fetal loss: a meta-analysis.
[object Object], [object Object], [object Object] et al. · Lancet · 2003
PMID: 12648968Meta-Analysis
Clinical, Laboratory, and Molecular Aspects of Factor V Deficiency.
[object Object], [object Object] · Semin Thromb Hemost · 2025
PMID: 39191405Review
Clinical, Laboratory, Molecular, and Reproductive Aspects of Combined Deficiency of Factors V and VIII.
[object Object], [object Object] · Semin Thromb Hemost · 2025
PMID: 39209292ReviewFull text (PMC)
The Magic of Proteases: From a Procoagulant and Anticoagulant Factor V to an Equitable Treatment of Its Inherited Deficiency.
[object Object], [object Object], [object Object] et al. · Int J Mol Sci · 2023
PMID: 37047215ReviewFull text (PMC)
A Review of Coagulation Abnormalities of Autoimmune Acquired Factor V Deficiency with a Focus on Japan.
[object Object], [object Object], [object Object] · Semin Thromb Hemost · 2022
PMID: 34942668Review
Congenital coagulation factor V deficiency with intracranial hemorrhage.
[object Object], [object Object], [object Object] · J Clin Lab Anal · 2022
PMID: 36125894ReviewFull text (PMC)
Inherited disorders of the fibrinolytic pathway.
[object Object], [object Object] · Transfus Apher Sci · 2019
PMID: 31427261Review
A Comprehensive Overview of Coagulation Factor V and Congenital Factor V Deficiency.
[object Object], [object Object], [object Object] et al. · Semin Thromb Hemost · 2019
PMID: 31121608Review
Platelet-delivered therapeutics.
[object Object], [object Object], [object Object] et al. · J Thromb Haemost · 2015
PMID: 26149015Review
Combined deficiency of coagulation factors V and VIII: an update.
[object Object], [object Object] · Semin Thromb Hemost · 2013
PMID: 23852824ReviewFull text (PMC)

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Joint hemorrhage
Frequent (30-79%)HP:0005261
Nasal hemorrhage
Frequent (30-79%)HP:0000421
Bleeding gums
Occasional (5-29%)HP:0000225
Blood in urine
Occasional (5-29%)HP:0000790
Bruising susceptibility
Occasional (5-29%)HP:0000978
Excessive bleeding after minor trauma
Occasional (5-29%)HP:0001934
Gastrointestinal haemorrhage
Occasional (5-29%)HP:0002239
Oral cavity bleeding
Occasional (5-29%)HP:0030140
Post-partum hemorrhage
Occasional (5-29%)HP:0011891
Prolonged bleeding after dental extraction
Occasional (5-29%)HP:0006298
Prolonged bleeding following circumcision
Occasional (5-29%)HP:0030137
Prolonged bleeding following procedure
Occasional (5-29%)HP:0011890
Protracted bleeding after surgery
Occasional (5-29%)HP:0004846
Spontaneous hematomas
Occasional (5-29%)HP:0007420
Abnormal uterus bleeding
Very rare (1-4%)HP:0100608
Haemoptysis
Very rare (1-4%)HP:0002105
Hematochezia
Very rare (1-4%)HP:0002573
Intracranial haemorrhage
Very rare (1-4%)HP:0002170
Bleeding tendency
HP:0001892
Hypermenorrhea
HP:0000132
Increased bleeding time
HP:0003010
Low factor II activity
HP:0008151
Prolonged activated partial thromboplastin time
HP:0003645
Prolonged whole-blood clotting time
HP:0005542
Reduced coagulation factor V activity
HP:0003225

Quick Facts

SNOMED CT
88776002
UMLS CUI
C0015499
Fully Specified Name
Hereditary factor V deficiency disease (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
25
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.