Treatments & Interventions
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Bone pain
Very frequent (80-99%)HP:0002653
Breakdown of bone
Very frequent (80-99%)HP:0002797
Coughing
Frequent (30-79%)HP:0012735
Dermatitis
Frequent (30-79%)HP:0000964
Enlarged liver
Frequent (30-79%)HP:0002240
Large spleen
Frequent (30-79%)HP:0001744
Pyrexia
Frequent (30-79%)HP:0001945
Skin rash
Frequent (30-79%)HP:0000988
Swollen lymph nodes
Frequent (30-79%)HP:0002716
Ataxia
Occasional (5-29%)HP:0001251
Diabetes insipidus
Occasional (5-29%)HP:0000873
Difficulty articulating speech
Occasional (5-29%)HP:0001260
Genital ulcers
Occasional (5-29%)HP:0003249
Growth deficiency
Occasional (5-29%)HP:0001510
Hypoacusis
Occasional (5-29%)HP:0000365
Intellectual deterioration
Occasional (5-29%)HP:0001268
Leukopenia
Occasional (5-29%)HP:0001882
Low albumin
Occasional (5-29%)HP:0003073
Mouth ulcer
Occasional (5-29%)HP:0000155
Pulmonary Langerhans cell histiocytosis
Occasional (5-29%)HP:0034769
Reduced circulating growth hormone concentration
Occasional (5-29%)HP:0034323
Spontaneous collapsed lung
Occasional (5-29%)HP:0002108
Thrombocytopenia
Occasional (5-29%)HP:0001873
Weight loss
Occasional (5-29%)HP:0001824
Fibrous cholangitis
Very rare (1-4%)HP:0030991
Hepatic failure
Very rare (1-4%)HP:0001399
Respiratory insufficiency
Very rare (1-4%)HP:0002093
Related Conditions
LSD - Letterer-Siwe disease(child)
Langerhans cell histiocytosis, unifocal (clinical)(child)
Langerhans cell histiocytosis - Hashimoto-Pritzker type(child)
Langerhans cell histiocytosis of lung(child)
Pulmonary hypertension in Langerhans cell histiocytosis(child)
Langerhans cell histiocytosis of skin(child)
Sinus histiocytosis with massive lymphadenopathy(child)
Dendritic cell neoplasm(parent)
Quick Facts
- SNOMED CT
- 65399007
- UMLS CUI
- C0019621
- Fully Specified Name
- Langerhans cell histiocytosis (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 27
- Known Treatments
- 1
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.