Hypercortisolism due to macronodular adrenal hyperplasia

disorder

SNOMED 720459002CUI C2062388

Overview

Hypercortisolism due to macronodular adrenal hyperplasia is a disorder.

Auto-generated from clinical reference data. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Macronodular adrenal hyperplasia

Always present (100%)HP:0008231

Decreased circulating ACTH concentration

Very frequent (80-99%)HP:0002920

Moon face

Very frequent (80-99%)HP:0500011

Abdominal obesity

Frequent (30-79%)HP:0012743

Abnormal glucose tolerance

Frequent (30-79%)HP:0001952

Abnormal libido

Frequent (30-79%)HP:0031845

Abnormal response to corticotropin releasing hormone stimulation test

Frequent (30-79%)HP:0031077

Bruising susceptibility

Frequent (30-79%)HP:0000978

Cushing syndrome

Frequent (30-79%)HP:0003118

Depressive episode

Frequent (30-79%)HP:0000716

Dorsocervical fat pad

Frequent (30-79%)HP:0025383

Emotional lability

Frequent (30-79%)HP:0000712

High blood pressure

Frequent (30-79%)HP:0000822

High urine cortisol level

Frequent (30-79%)HP:0012030

Hirsutism

Frequent (30-79%)HP:0001007

Hyperlipidemia

Frequent (30-79%)HP:0003077

Kidney stones

Frequent (30-79%)HP:0000787

Menstrual irregularity

Frequent (30-79%)HP:0000858

Osteoporosis

Frequent (30-79%)HP:0000939

Paradoxical increased cortisol secretion on dexamethasone suppression test

Frequent (30-79%)HP:0003466

Plethora

Frequent (30-79%)HP:0001050

Proximal limb muscle weakness

Frequent (30-79%)HP:0003701

Striae atrophicae

Frequent (30-79%)HP:0001065

Symmetrical, proximal limb muscle atrophy

Frequent (30-79%)HP:0007126

Breaking out

Occasional (5-29%)HP:0001061

Fatty liver

Occasional (5-29%)HP:0001397

Hair loss

Occasional (5-29%)HP:0001596

Increased body weight

Occasional (5-29%)HP:0004324

Increased susceptibility to fractures

Occasional (5-29%)HP:0002659

Manic

Occasional (5-29%)HP:0100754

Related Conditions

Hypercortisolism(parent)

Quick Facts

SNOMED CT: 720459002
UMLS CUI: C2062388
Fully Specified Name: Hypercortisolism due to macronodular adrenal hyperplasia (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.