Overview
Limbal stem cell deficiency is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Research Evidence
Peer-reviewed studies linked via MeSH term "Limbal Stem Cell Deficiency" from the MEDLINE/PubMed database.
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Demographics of Limbal Stem Cell Deficiency: A Literature Review.
[object Object], [object Object], [object Object] · Eye Contact Lens · 2025
PMID: 40209219Review
Pediatric limbal stem cell deficiency: An overview of a rarely studied pathology.
[object Object], [object Object] · Eur J Ophthalmol · 2025
PMID: 39473431Review
Limbal stem cell deficiency approaches and limbal niche restoration.
[object Object], [object Object], [object Object] et al. · Indian J Ophthalmol · 2025
[Autologous oral mucosal epithelial transplantation in the treatment of bilateral limbal stem cell deficiency].
[object Object], [object Object], [object Object] et al. · Vestn Oftalmol · 2025
PMID: 40920164Review
Advances in the Diagnosis and Management of Limbal Stem Cell Deficiency.
[object Object], [object Object], [object Object] et al. · Cornea · 2025
Biology and medicine on ocular surface restoration: Advancements and limits of limbal stem cell deficiency treatments.
[object Object], [object Object], [object Object] et al. · Ocul Surf · 2025
PMID: 39580144Review
Biologicals and Biomaterials for Corneal Regeneration and Vision Restoration in Limbal Stem Cell Deficiency.
[object Object] · Adv Mater · 2024
PMID: 38777343Review
Advances in Cell Transplantation Therapy for Limbal Stem Cell Deficiency.
[object Object], [object Object], [object Object] et al. · Curr Stem Cell Res Ther · 2024
PMID: 37605422Review
Why Are Corneal Specialists Resistant to Treating Patients Who Have Severe Ocular Surface Disease With Limbal Stem Cell Deficiency?
[object Object], [object Object], [object Object] et al. · Cornea · 2023
PMID: 37535943Review
[Research progress on imagine diagnosis of limbal stem cell deficiency].
[object Object], [object Object] · Zhonghua Yan Ke Za Zhi · 2023
PMID: 37550976Review
Search all PubMed articles for Limbal stem cell deficiency
Research data from MEDLINE/PubMed
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormality of tear production
Frequent (30-79%)HP:0000632
Conjunctival hyperemia
Frequent (30-79%)HP:0030953
Decreased visual acuity
Frequent (30-79%)HP:0007663
Eye pain
Frequent (30-79%)HP:0200026
Increased lacrimation
Frequent (30-79%)HP:0009926
Involuntary closure of eyelid
Frequent (30-79%)HP:0000643
Photophobia
Frequent (30-79%)HP:0000613
Reduced corneal reflex
Frequent (30-79%)HP:0008000
Corneal inflammation
Occasional (5-29%)HP:0000491
Corneal pannus
Occasional (5-29%)HP:0011496
Corneal scarring
Occasional (5-29%)HP:0000559
Generalized opacification of the cornea
Occasional (5-29%)HP:0011494
Opacification of the corneal epithelium
Occasional (5-29%)HP:0007727
Corneal perforation
Very rare (1-4%)HP:0100583
Vortex keratopathy
Very rare (1-4%)HP:0500008
Quick Facts
- SNOMED CT
- 417089009
- UMLS CUI
- C1561989
- Fully Specified Name
- Limbal stem cell deficiency (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 15
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.