Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Feeding difficulties
Very frequent (80-99%)HP:0011968
Ocular hypotelorism
Very frequent (80-99%)HP:0000601
Abnormal central motor function
Frequent (30-79%)HP:0011442
Abnormal hypothalamus physiology
Frequent (30-79%)HP:0012285
Abnormality of the autonomic nervous system
Frequent (30-79%)HP:0002270
Anxiety disease
Frequent (30-79%)HP:0000739
Aspiration pneumonia
Frequent (30-79%)HP:0011951
Behavioral changes
Frequent (30-79%)HP:0000708
Childhood attention deficit/hyperactivity disorder
Frequent (30-79%)HP:0007018
Chronic lung disease
Frequent (30-79%)HP:0006528
Cleft of palate
Frequent (30-79%)HP:0000175
Constipation
Frequent (30-79%)HP:0002019
Decreased body height
Frequent (30-79%)HP:0004322
Depression
Frequent (30-79%)HP:0000716
Diabetes insipidus
Frequent (30-79%)HP:0000873
Difficulty speaking
Frequent (30-79%)HP:0002465
Endocrine system disease
Frequent (30-79%)HP:0000818
Eye disease
Frequent (30-79%)HP:0000478
Gastro-esophageal reflux
Frequent (30-79%)HP:0002020
Growth failure
Frequent (30-79%)HP:0001510
High arched palate
Frequent (30-79%)HP:0000218
Internal-clock disorders
Frequent (30-79%)HP:0006979
Irritability
Frequent (30-79%)HP:0000737
Midline cleft lip
Frequent (30-79%)HP:0000161
Nonprogressive mental retardation
Frequent (30-79%)HP:0001249
Poor sucking
Frequent (30-79%)HP:0002033
Retruded nasal dorsum
Frequent (30-79%)HP:0000457
Sensorineural deafness
Frequent (30-79%)HP:0000407
Specific learning disability
Frequent (30-79%)HP:0001328
Undergrowth
Frequent (30-79%)HP:0001508
Related Conditions
Quick Facts
- SNOMED CT
- 253136007
- UMLS CUI
- C0431362
- Fully Specified Name
- Lobar holoprosencephaly (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.