Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormal compact bone morphology
Very frequent (80-99%)HP:0003103
Abnormal metaphysis morphology
Very frequent (80-99%)HP:0000944
Bowed long bones
Very frequent (80-99%)HP:0006487
Decreased body height
Very frequent (80-99%)HP:0004322
Delayed closure of the fontanelles
Very frequent (80-99%)HP:0000270
Hyperplasia of supraorbital ridge
Very frequent (80-99%)HP:0000336
Increased distance between eyes
Very frequent (80-99%)HP:0000316
Low chest circumference
Very frequent (80-99%)HP:0000774
Prominent globes
Very frequent (80-99%)HP:0000520
Shorter than typical length between neck and abdomen
Very frequent (80-99%)HP:0010306
Abnormal pubic bone morphology
Frequent (30-79%)HP:0003172
Abnormality of position of teeth
Frequent (30-79%)HP:0000692
Anisospondyly
Frequent (30-79%)HP:0002879
Big cheeks
Frequent (30-79%)HP:0000293
Cone-shaped epiphyses of the fingers
Frequent (30-79%)HP:0010230
Coxa valga deformity
Frequent (30-79%)HP:0002673
Delayed eruption of teeth
Frequent (30-79%)HP:0000684
Dislocated femoral heads
Frequent (30-79%)HP:0002827
Distal phalangeal hypoplasia
Frequent (30-79%)HP:0009882
Frontal protuberance
Frequent (30-79%)HP:0002007
Hearing impairment
Frequent (30-79%)HP:0000365
Heart septal defect
Frequent (30-79%)HP:0001671
Hydronephrosis
Frequent (30-79%)HP:0000126
Loose-jointedness
Frequent (30-79%)HP:0001382
Osteolytic defects of the phalanges of the hand
Frequent (30-79%)HP:0009771
respiratory infections, recurrent
Frequent (30-79%)HP:0002205
Rib anomalies
Frequent (30-79%)HP:0000772
Scoliosis
Frequent (30-79%)HP:0002650
Short clavicles
Frequent (30-79%)HP:0000894
Thick craniofacial bones
Frequent (30-79%)HP:0004493
Quick Facts
- SNOMED CT
- 13449007
- UMLS CUI
- C0025237
- Fully Specified Name
- Melnick-Needles syndrome (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.