Obliterative bronchiolitis

disorder

SNOMED 40100001CUI C0006272

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Clinical Trials

Total Trials

Recruiting

With Results

Recent Trials

Ruxolitinib for Early Lung Dysfunction After Hematopoietic Stem Cell Transplant

NCT04908735Phase 2Active Not Recruiting7 enrolled

Vitamin D in Bronchiolitis Obliterans Syndrome

NCT01212406Phase 4Completed100 enrolled

Efficacy and Safety of Azithromycin in Patients With Bronchiolitis Obliterans

NCT05299567Phase 4Completed40 enrolled

Montelukast in Bronchiolitis Obliterans Syndrome

NCT01211509Phase 4Completed30 enrolled

Bronchodilator Responsiveness in Obliterative Bronchiolitis

NCT01112241Phase 4Completed17 enrolled

View all 6 trials on ClinicalTrials.gov

Research Evidence

Peer-reviewed studies linked via MeSH term "Bronchiolitis Obliterans" from the MEDLINE/PubMed database.

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Treatment Options for Bronchiolitis Obliterans Secondary to Hematopoietic Cell Transplantation in Children: A Systematic Review.

[object Object], [object Object], [object Object] et al. · Clin Transplant · 2025

PMID: 40794819Meta-Analysis

Interventional anti-reflux management for gastro-oesophageal reflux disease in lung transplant recipients: a systematic review and meta-analysis.

[object Object], [object Object], [object Object] et al. · Surg Endosc · 2025

PMID: 39586876Meta-AnalysisFull text (PMC)

Risk factors for bronchiolitis obliterans syndrome after hematopoietic stem cell transplantation: a systematic review and meta-analysis.

[object Object], [object Object], [object Object] et al. · BMC Pulm Med · 2025

PMID: 41039440Meta-AnalysisFull text (PMC)

Pulmonary function testing in pediatric allogeneic stem cell transplant recipients to monitor for Bronchiolitis obliterans syndrome: a systematic review.

[object Object], [object Object], [object Object] et al. · BMC Pediatr · 2025

PMID: 40155876Meta-AnalysisFull text (PMC)

Effect of azithromycin on bronchiolitis obliterans syndrome in posttransplant recipients: A systematic review and meta-analysis.

[object Object], [object Object], [object Object] et al. · Medicine (Baltimore) · 2022

PMID: 35839027Meta-AnalysisFull text (PMC)

Fundoplication to preserve allograft function after lung transplant: Systematic review and meta-analysis.

[object Object], [object Object], [object Object] et al. · J Thorac Cardiovasc Surg · 2020

PMID: 31928822Meta-Analysis

Risk factors for death and survival in paraneoplastic pemphigus associated with hematologic malignancies in adults.

[object Object], [object Object], [object Object] et al. · J Am Acad Dermatol · 2019

PMID: 30981429Meta-Analysis

Constrictive Bronchiolitis Attributable to Inhalation of Toxic Agents: Considerations for a Case Definition.

[object Object], [object Object], [object Object] et al. · J Occup Environ Med · 2018

PMID: 28953074Meta-Analysis

Azithromycin for the Treatment of Obliterative Bronchiolitis after Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis.

[object Object], [object Object], [object Object] et al. · Biol Blood Marrow Transplant · 2016

PMID: 27575542Meta-AnalysisFull text (PMC)

Chronic Lung Allograft Dysfunction: A Systematic Review of Mechanisms.

[object Object], [object Object], [object Object] et al. · Transplantation · 2016

PMID: 27257997Meta-Analysis

Search all PubMed articles for Obliterative bronchiolitis

Research data from MEDLINE/PubMed

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Constrictive bronchiolitis

Very frequent (80-99%)HP:0011946

Coughing

Very frequent (80-99%)HP:0012735

Decreased FEF25-75%

Very frequent (80-99%)HP:0032359

Hypoxia

Very frequent (80-99%)HP:0012418

Panting

Very frequent (80-99%)HP:0002094

Pulmonary obstruction

Very frequent (80-99%)HP:0006536

Reduced FEV1

Very frequent (80-99%)HP:0032342

Reduced FEV1/FVC ratio

Very frequent (80-99%)HP:0030877

Reduced forced vital capacity

Very frequent (80-99%)HP:0032341

Decreased DLCO

Frequent (30-79%)HP:0045051

Nonproductive cough

Frequent (30-79%)HP:0031246

Pneumonia

Frequent (30-79%)HP:0002090

Respiratory infection

Frequent (30-79%)HP:0011947

Autoimmunity

Occasional (5-29%)HP:0002960

Bronchiectasis

Occasional (5-29%)HP:0002110

Ground-glass opacification

Very rare (1-4%)HP:0025179

Related Conditions

Toxic bronchiolitis obliterans(child)

Drug-induced bronchiolitis obliterans(child)

Subacute obliterative bronchiolitis(child)

Chronic obliterative bronchiolitis(child)

Acute obliterating bronchiolitis(child)

Bronchiolitis(parent)

Quick Facts

SNOMED CT: 40100001
UMLS CUI: C0006272
Fully Specified Name: Obliterative bronchiolitis (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 16
Clinical Trials: 6

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.