Overview
Papillon-Lefèvre syndrome is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormality of the fingernails
Very frequent (80-99%)HP:0001231
Alveolar bone loss
Very frequent (80-99%)HP:0006308
Dental agenesis
Very frequent (80-99%)HP:0009804
Dental problems
Very frequent (80-99%)HP:0000164
Keratoderma
Very frequent (80-99%)HP:0000982
Palmoplantar keratosis
Very frequent (80-99%)HP:0000972
Premature exfoliation of primary teeth
Very frequent (80-99%)HP:0006323
Pustules
Very frequent (80-99%)HP:0200039
Pyorrhea
Very frequent (80-99%)HP:0000704
Red and swollen gums
Very frequent (80-99%)HP:0000230
Severe pyorrhea
Very frequent (80-99%)HP:0000166
Abnormal deposits of calcium in the brain
Frequent (30-79%)HP:0002514
Abnormal nail morphology
Frequent (30-79%)HP:0001597
Chronic furunculosis
Frequent (30-79%)HP:0011132
Dystrophic nails
Frequent (30-79%)HP:0008404
Recurrent cutaneous abscess formation
Frequent (30-79%)HP:0100838
respiratory infections, recurrent
Frequent (30-79%)HP:0002205
Skin infections, recurrent
Frequent (30-79%)HP:0001581
Arachnodactyly
Occasional (5-29%)HP:0001166
Breakdown of bone
Occasional (5-29%)HP:0002797
Cigarette-paper scars
Occasional (5-29%)HP:0001073
Generalized hirsutism
Occasional (5-29%)HP:0002230
Hypertrichosis
Occasional (5-29%)HP:0000998
Hypopigmented skin patches
Occasional (5-29%)HP:0001053
Liver abscess
Occasional (5-29%)HP:0100523
Melanoma
Occasional (5-29%)HP:0002861
Neoplasm of the skin
Occasional (5-29%)HP:0008069
Sparse body hair
Occasional (5-29%)HP:0002231
Squamous cell cancer
Occasional (5-29%)HP:0002860
Choroid plexus calcification
HP:0006960
Related Conditions
Hereditary disorder of musculoskeletal system(parent)
Recessive hereditary disorder (autosomal)(parent)
Digestive system hereditary disorder(parent)
Alveolar bone loss(parent)
Congenital anomaly of jaw(parent)
Congenital abnormality of hand and digits(parent)
Ectodermal dysplasia(parent)
Hereditary diffuse palmoplantar keratoderma(parent)
Congenital deformity and malformation of feet and toes(parent)
Congenital anomaly of face bones(parent)
Developmental hereditary disorder(parent)
Congenital abnormality of oral cavity(parent)
Congenital anomaly of digestive organ(parent)
Abnormal jaw bone morphology(parent)
Quick Facts
- SNOMED CT
- 40158001
- UMLS CUI
- C0030360
- Fully Specified Name
- Papillon-Lefèvre syndrome (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.