Pineal hyperplasia AND diabetes mellitus syndrome

disorder

SNOMED 33559001CUI C0271695

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Acanthosis nigricans

Frequent (30-79%)HP:0000956

Body fails to respond to insulin

Frequent (30-79%)HP:0000855

Decreased body height

Frequent (30-79%)HP:0004322

Dental anomalies

Frequent (30-79%)HP:0000164

Dull intelligence

Frequent (30-79%)HP:0001249

Enlarged ovaries

Frequent (30-79%)HP:0100879

Fasting hyperinsulinemia

Frequent (30-79%)HP:0008283

Hirsutism

Frequent (30-79%)HP:0001007

Hypertrichosis

Frequent (30-79%)HP:0000998

Increased C-peptide level

Frequent (30-79%)HP:0030796

Increased circulating androgen concentration

Frequent (30-79%)HP:0030348

Increased testosterone

Frequent (30-79%)HP:0030088

Insulin-resistant diabetes

Frequent (30-79%)HP:0000831

Lichenoid skin lesion

Frequent (30-79%)HP:0031452

Long penis

Frequent (30-79%)HP:0000040

Low blood sugar when fasting

Frequent (30-79%)HP:0003162

Marked growth retardation

Frequent (30-79%)HP:0008850

Mental and motor retardation

Frequent (30-79%)HP:0001263

Postprandial hyperglycemia

Frequent (30-79%)HP:0011998

Predisposition to infections

Frequent (30-79%)HP:0002719

Prominent clitoris

Frequent (30-79%)HP:0008665

Reduced subcutaneous adipose tissue

Frequent (30-79%)HP:0003758

Small for gestational age infant

Frequent (30-79%)HP:0001511

Thick hair

Frequent (30-79%)HP:0100874

Tooth mass arch size discrepancy

Frequent (30-79%)HP:0000678

Xerosis

Frequent (30-79%)HP:0000958

Atria septal defect

Occasional (5-29%)HP:0001631

Delayed skeletal development

Occasional (5-29%)HP:0002750

Demyelination in central white matter

Occasional (5-29%)HP:0007305

Diabetic ketoacidosis

Occasional (5-29%)HP:0001953

Related Conditions

Diabetes mellitus associated with genetic syndrome(parent)

Diabetes mellitus due to genetic defect in insulin action(parent)

Central nervous system complication(parent)

Abnormality of pineal gland morphology(parent)

Quick Facts

SNOMED CT: 33559001
UMLS CUI: C0271695
Fully Specified Name: Pineal hyperplasia AND diabetes mellitus syndrome (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.