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Progressive supranuclear palsy

disorder
SNOMED 192976002CUI C0038868

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Degeneration of cerebrum
Always present (100%)HP:0002059
Increase in astrocyte number
Always present (100%)HP:0002446
Micrographia
Always present (100%)HP:0031908
Senile plaques
Always present (100%)HP:0100256
Tau-positive tangle
Always present (100%)HP:0002185
Abnormal synaptic transmission
Very frequent (80-99%)HP:0012535
Deglutition disorder
Very frequent (80-99%)HP:0002015
Falls
Very frequent (80-99%)HP:0002527
Imbalance
Very frequent (80-99%)HP:0002172
Impulsivity
Very frequent (80-99%)HP:0100710
Intellectual deterioration
Very frequent (80-99%)HP:0001268
Neuronal loss in CNS
Very frequent (80-99%)HP:0002529
Supranuclear ophthalmoplegia
Very frequent (80-99%)HP:0000623
Unsteady walk
Very frequent (80-99%)HP:0002317
Abnormal saccadic eye movements
Frequent (30-79%)HP:0000570
Abnormality of balance
Frequent (30-79%)HP:0002141
Axial dystonia
Frequent (30-79%)HP:0002530
Blurred vision
Frequent (30-79%)HP:0000622
Cerebral cortex atrophy
Frequent (30-79%)HP:0002120
Conjunctival hyperemia
Frequent (30-79%)HP:0030953
Decreased tear secretion
Frequent (30-79%)HP:0000633
Depressive episode
Frequent (30-79%)HP:0000716
Difficulty articulating speech
Frequent (30-79%)HP:0001260
Difficulty finding words
Frequent (30-79%)HP:0002381
Dizziness
Frequent (30-79%)HP:0002321
Emotional lability
Frequent (30-79%)HP:0000712
Excess astrocytes in brain
Frequent (30-79%)HP:0002171
Impaired vision
Frequent (30-79%)HP:0000505
Intellectual impairment
Frequent (30-79%)HP:0100543
Involuntary closure of eyelid
Frequent (30-79%)HP:0000643

Related Conditions

Atypical progressive supranuclear palsy syndrome(child)
Ophthalmoplegia(parent)
Cerebral degeneration(parent)
Supranuclear gaze palsy(parent)
Genetic disease(parent)
Chronic brain syndrome(parent)

Quick Facts

SNOMED CT
192976002
UMLS CUI
C0038868
Fully Specified Name
Progressive supranuclear palsy (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
30
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.