Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Abnormal eye
Very frequent (80-99%)HP:0000478
Decreased body height
Very frequent (80-99%)HP:0004322
Feeding difficulties
Very frequent (80-99%)HP:0011968
Ocular hypotelorism
Very frequent (80-99%)HP:0000601
Poor growth
Very frequent (80-99%)HP:0001510
Poor sucking
Very frequent (80-99%)HP:0002033
Postnatal failure to thrive
Very frequent (80-99%)HP:0001508
Abnormal central motor function
Frequent (30-79%)HP:0011442
Abnormal hypothalamus physiology
Frequent (30-79%)HP:0012285
Abnormal morphology of the olfactory bulb
Frequent (30-79%)HP:0040327
Abnormal respiratory patterns
Frequent (30-79%)HP:0002793
Abnormality of brainstem morphology
Frequent (30-79%)HP:0002363
Abnormality of the autonomic nervous system
Frequent (30-79%)HP:0002270
Aplasia of the falx cerebri
Frequent (30-79%)HP:0010654
Aspiration pneumonia
Frequent (30-79%)HP:0011951
Behavioural/Psychiatric abnormality
Frequent (30-79%)HP:0000708
Central apnoea
Frequent (30-79%)HP:0002871
Childhood attention deficit/hyperactivity disorder
Frequent (30-79%)HP:0007018
Chronic lung disease
Frequent (30-79%)HP:0006528
Cleft of palate
Frequent (30-79%)HP:0000175
CVI
Frequent (30-79%)HP:0100704
Decreased size of cranium
Frequent (30-79%)HP:0000252
Deglutition disorder
Frequent (30-79%)HP:0002015
Depression
Frequent (30-79%)HP:0000716
Dyschezia
Frequent (30-79%)HP:0002019
Epilepsy
Frequent (30-79%)HP:0001250
Excessive, persistent worry and fear
Frequent (30-79%)HP:0000739
Gastroesophageal reflux disease
Frequent (30-79%)HP:0002020
High arched palate
Frequent (30-79%)HP:0000218
Hypotonia, early
Frequent (30-79%)HP:0008947
Related Conditions
Quick Facts
- SNOMED CT
- 253138008
- UMLS CUI
- C0751617
- Fully Specified Name
- Semi-lobar holoprosencephaly (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.