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Sicca syndrome

disorder
SNOMED 83901003CUI C1527336

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Treatments & Interventions

Research Evidence

Peer-reviewed studies linked via MeSH term "Sjogren's Syndrome" from the MEDLINE/PubMed database.

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Explore the possible influence of Sjogren's syndrome on thyroid cancer: A literature data mining and meta-analysis.
[object Object], [object Object], [object Object] et al. · PLoS One · 2025
PMID: 39928612Meta-AnalysisFull text (PMC)
Effects of exercise in primary Sjögren's syndrome: a systematic review and meta-analysis of randomized clinical trials.
[object Object], [object Object], [object Object] · Disabil Rehabil · 2025
PMID: 40062666Meta-Analysis
Sjögren's Syndrome and Ankylosing Spondylitis Association: A Case-Based Review.
[object Object], [object Object], [object Object] et al. · Curr Rheumatol Rev · 2025
PMID: 39506443Meta-Analysis
Association between oral microbiome dysbiosis and Sjogren Syndrome. A systematic review of clinical studies.
[object Object], [object Object], [object Object] et al. · Arch Oral Biol · 2025
PMID: 39798503Meta-Analysis
Recommendations on neurologic, cognitive, and psychiatric manifestations in patients with Sjögren's disease by the Brazilian Society of Rheumatology.
[object Object], [object Object], [object Object] et al. · Adv Rheumatol · 2025
PMID: 39934881Meta-Analysis
Risk relationship between six autoimmune diseases and malignancies: An umbrella review.
[object Object], [object Object], [object Object] et al. · Autoimmun Rev · 2025
PMID: 39983807Meta-Analysis
Sjogren's syndrome due to immune checkpoint inhibitors (ICIs): Insights from a single-institution series and systematic review of the literature.
[object Object], [object Object], [object Object] et al. · J Oncol Pharm Pract · 2025
PMID: 39113536Meta-Analysis
Meta-analysis of mortality-associated factors in primary Sjögren's syndrome patients with interstitial lung disease.
[object Object], [object Object], [object Object] et al. · Clin Rheumatol · 2025
PMID: 39432139Meta-AnalysisFull text (PMC)
Associations Between Interleukin-10 Polymorphisms and Susceptibility to Sjögren's Syndrome: A Meta-Analysis.
[object Object], [object Object] · Int J Immunogenet · 2025
PMID: 39511968Meta-Analysis
Expression of interleukin-18 in primary Sjögren syndrome and its potential mechanisms with disease: A systematic review and meta-analysis.
[object Object], [object Object], [object Object] et al. · Medicine (Baltimore) · 2025
PMID: 40128067Meta-AnalysisFull text (PMC)
Search all PubMed articles for Sicca syndrome

Research data from MEDLINE/PubMed

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Anti-Ro/SSA antibody positivity
Very frequent (80-99%)HP:0033555
Xerostomia
Very frequent (80-99%)HP:0000217
Anti-La/SS-B antibody positivity
Frequent (30-79%)HP:0032235
Arthralgias
Frequent (30-79%)HP:0002829
Cryoglobulinemia
Frequent (30-79%)HP:0100778
Decreased serum complement C4 level
Frequent (30-79%)HP:0045042
Elevated C-reactive protein level
Frequent (30-79%)HP:0011227
Elevated sedimentation rate
Frequent (30-79%)HP:0003565
Increased circulating globulin level
Frequent (30-79%)HP:0032311
Raynaud disease
Frequent (30-79%)HP:0030880
Rheumatoid factor positive
Frequent (30-79%)HP:0002923
Skin rash
Frequent (30-79%)HP:0000988
Xerophthalmia
Frequent (30-79%)HP:0001097
Autoimmune disorder
HP:0002960
Hyperplasia of parotid gland
HP:0011801
Rheumatoid arthritis
HP:0001370
Tubulointerstitial nephritis
HP:0001970

Quick Facts

SNOMED CT
83901003
UMLS CUI
C1527336
Fully Specified Name
Sjögren's syndrome (disorder)
Specialists
0
Diagnostic Biomarkers
0
HPO Phenotypes
17
Known Treatments
1
Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.