Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Spastic walk
Very frequent (80-99%)HP:0002064
Abnormal mitochondrial morphology
Frequent (30-79%)HP:0008322
Abnormality of mental function
Frequent (30-79%)HP:0011446
Childhood attention deficit/hyperactivity disorder
Frequent (30-79%)HP:0007018
Corticospinal signs
Frequent (30-79%)HP:0007256
Distal sensory loss, especially vibratory sense
Frequent (30-79%)HP:0002166
Extensor plantar responses
Frequent (30-79%)HP:0003487
Infratentorial atrophy
Frequent (30-79%)HP:0001272
Involuntary, rapid, rhythmic eye movements
Frequent (30-79%)HP:0000639
Lower limb hyperreflexia
Frequent (30-79%)HP:0002395
Lower limb hypertonia
Frequent (30-79%)HP:0006895
Lower limb muscle weakness
Frequent (30-79%)HP:0007340
Nasal speech
Frequent (30-79%)HP:0001611
Optic atrophy
Frequent (30-79%)HP:0000648
Ragged-red muscle fibers
Frequent (30-79%)HP:0003200
Sensory impairment
Frequent (30-79%)HP:0003474
Slowed slurred speech
Frequent (30-79%)HP:0007164
Supranuclear gaze paralysis
Frequent (30-79%)HP:0000605
Urgency frequency syndrome
Frequent (30-79%)HP:0000012
Abnormality of the cerebral white matter
Occasional (5-29%)HP:0002500
Cavus foot
Occasional (5-29%)HP:0001761
Cerebral cortex atrophy
Occasional (5-29%)HP:0002120
Difficulty articulating speech
Occasional (5-29%)HP:0001260
Optic disc pallor
Occasional (5-29%)HP:0000543
Scoliosis
Occasional (5-29%)HP:0002650
Upper limb muscle weakness
Occasional (5-29%)HP:0003484
Deglutition disorder
Very rare (1-4%)HP:0002015
Lower limb pain
Very rare (1-4%)HP:0012514
Memory impairment
Very rare (1-4%)HP:0002354
Specific learning disability
Very rare (1-4%)HP:0001328
Quick Facts
- SNOMED CT
- 715776003
- UMLS CUI
- C3711370
- Fully Specified Name
- Spastic paraplegia type 7 (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 30
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.