Sporadic Creutzfeldt-Jakob disease

disorder

SNOMED 713060000CUI C1852467

Overview

Sporadic Creutzfeldt-Jakob disease is a disorder.

Auto-generated from clinical reference data. Not a substitute for medical advice.

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Akinetic mutism

Very frequent (80-99%)HP:0012672

Cerebral cortex with spongiform changes

Very frequent (80-99%)HP:0006790

Hyperintensity of cerebral white matter on MRI

Very frequent (80-99%)HP:0030890

Neuronal loss in CNS

Very frequent (80-99%)HP:0002529

Ataxia

Frequent (30-79%)HP:0001251

Behavioral symptoms

Frequent (30-79%)HP:0000708

Cerebral atrophy

Frequent (30-79%)HP:0002059

Cognitive deficits

Frequent (30-79%)HP:0100543

Elevated csf protein

Frequent (30-79%)HP:0002922

Excess astrocytes in brain

Frequent (30-79%)HP:0002171

Hypsarrhythmia by EEG

Frequent (30-79%)HP:0002521

Increase in astrocyte number

Frequent (30-79%)HP:0002446

Infection in blood stream

Frequent (30-79%)HP:0100806

Memory impairment

Frequent (30-79%)HP:0002354

Predisposition to infections

Frequent (30-79%)HP:0002719

Recurrent aspiration pneumonia

Frequent (30-79%)HP:0002100

Respiratory distress requiring endotracheal intubation

Frequent (30-79%)HP:0004887

Visual hallucination

Frequent (30-79%)HP:0002367

Corticospinal signs

Occasional (5-29%)HP:0007256

Depressive episode

Occasional (5-29%)HP:0000716

Emotional lability

Occasional (5-29%)HP:0000712

Extensor plantar responses

Occasional (5-29%)HP:0003487

Extrapyramidal syndrome

Occasional (5-29%)HP:0002071

Headache

Occasional (5-29%)HP:0002315

Hyperactive deep tendon reflexes

Occasional (5-29%)HP:0006801

Involuntary muscle stiffness, contraction, or spasm

Occasional (5-29%)HP:0001257

Irritable mood

Occasional (5-29%)HP:0000737

Loss of speech

Occasional (5-29%)HP:0002371

Pyramidal tract dysfunction

Occasional (5-29%)HP:0002493

Tiredness

Occasional (5-29%)HP:0012378

Related Conditions

Classical sporadic Creutzfeldt-Jakob disease(child)

Sporadic fatal insomnia(child)

Jakob-Creutzfeldt disease(parent)

Quick Facts

SNOMED CT: 713060000
UMLS CUI: C1852467
Fully Specified Name: Sporadic Creutzfeldt-Jakob disease (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 30

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.