von Willebrand disease type 1

disorder

SNOMED 128106003CUI C1264039

Overview

Source: MedlinePlus.gov, National Library of Medicine. Not a substitute for medical advice.

Research Evidence

Peer-reviewed studies linked via MeSH term "von Willebrand Disease, Type 1" from the MEDLINE/PubMed database.

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von Willebrand factor levels in the diagnosis of von Willebrand disease: a systematic review and meta-analysis.

[object Object], [object Object], [object Object] et al. · Blood Adv · 2022

PMID: 34610118Meta-AnalysisFull text (PMC)

Postpartum Hemorrhage in Patients with Type 1 von Willebrand Disease: A Systematic Review.

[object Object], [object Object], [object Object] et al. · Semin Thromb Hemost · 2022

PMID: 34749402Meta-Analysis

Impact of tranexamic acid on postpartum hemorrhage in type 1 von Willebrand disease treated with recombinant VWF.

[object Object], [object Object], [object Object] et al. · Blood Adv · 2025

PMID: 40902088RCTFull text (PMC)

Low von Willebrand factor-unraveling an enigma wrapped in a conundrum.

[object Object], [object Object], [object Object] · J Thromb Haemost · 2024

PMID: 39265913ReviewFull text (PMC)

Clinical significance of slightly reduced von Willebrand factor activity.

[object Object], [object Object] · Pol Arch Intern Med · 2020

PMID: 31990275Review

Low VWF: insights into pathogenesis, diagnosis, and clinical management.

[object Object] · Blood Adv · 2020

PMID: 32663299ReviewFull text (PMC)

How I treat von Willebrand disease.

[object Object] · Thromb Res · 2020

PMID: 32819724Review

The role of genetics in the pathogenesis and diagnosis of type 1 Von Willebrand disease.

[object Object], [object Object], [object Object] · Curr Opin Hematol · 2019

PMID: 31261173ReviewFull text (PMC)

Diagnostic challenges of inherited mild bleeding disorders: a bait for poorly explored clinical and basic research.

[object Object], [object Object] · J Thromb Haemost · 2019

PMID: 30562407Review

How I treat low von Willebrand factor levels.

[object Object], [object Object] · Blood · 2019

PMID: 30578256Review

Search all PubMed articles for von Willebrand disease type 1

Research data from MEDLINE/PubMed

Signs & Symptoms

Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.

Bruising susceptibility

Frequent (30-79%)HP:0000978

Excessive bleeding after minor trauma

Frequent (30-79%)HP:0001934

Frequent nosebleeds

Frequent (30-79%)HP:0000421

Prolonged bleeding after dental extraction

Frequent (30-79%)HP:0006298

Protracted bleeding after surgery

Frequent (30-79%)HP:0004846

Aortic stenosis

HP:0001650

Factor VIII deficiency

HP:0003125

Gastrointestinal angiodysplasia

HP:0000471

Gastrointestinal haemorrhage

HP:0002239

Hypermenorrhea

HP:0000132

Impaired platelet aggregation

HP:0003540

Increased bleeding time

HP:0003010

Joint hemorrhage

HP:0005261

Mitral valve prolapse

HP:0001634

Prolonged whole-blood clotting time

HP:0005542

Reduced quantity of Von Willebrand factor

HP:0012147

Related Conditions

von Willebrand disease type IC(child)

von Willebrand disease type IB(child)

Hereditary von Willebrand disease type IA(child)

Autosomal dominant hereditary disorder(parent)

Hereditary von Willebrand disease(parent)

Quick Facts

SNOMED CT: 128106003
UMLS CUI: C1264039
Fully Specified Name: Hereditary von Willebrand disease type 1 (disorder)
Specialists: 0
Diagnostic Biomarkers: 0
HPO Phenotypes: 16

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.