Overview
Wolfram-like syndrome is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
ASD
Very frequent (80-99%)HP:0000729
Depressive episode
Very frequent (80-99%)HP:0000716
Diabetes mellitus
Very frequent (80-99%)HP:0000819
Excessive, persistent worry and fear
Very frequent (80-99%)HP:0000739
Optic atrophy
Very frequent (80-99%)HP:0000648
Progressive dementia
Very frequent (80-99%)HP:0000726
Psychosis
Very frequent (80-99%)HP:0000709
Abnormal glucose tolerance
Frequent (30-79%)HP:0001952
Abnormality of the upper urinary tract
Frequent (30-79%)HP:0010935
Bilateral congenital sensorineural deafness
Frequent (30-79%)HP:0008527
Decreased function of male gonad
Frequent (30-79%)HP:0000026
Delayed puberty
Frequent (30-79%)HP:0000823
Dysplastic ears
Frequent (30-79%)HP:0000377
GI dysmotility
Frequent (30-79%)HP:0002579
Glaucoma
Frequent (30-79%)HP:0000501
Neurohypophyseal diabetes insipidus
Frequent (30-79%)HP:0000863
Peripheral axonal neuropathy
Frequent (30-79%)HP:0003477
Primary gonadal insufficiency
Frequent (30-79%)HP:0008193
Progressive cerebellar ataxia
Frequent (30-79%)HP:0002073
Hypothyroidism
Occasional (5-29%)HP:0000821
Marked growth retardation
Occasional (5-29%)HP:0008850
Respiratory insufficiency
Occasional (5-29%)HP:0002093
Related Conditions
Diabetes mellitus associated with genetic syndrome(parent)
Autosomal dominant hereditary disorder(parent)
Hereditary optic atrophy(parent)
Hearing loss associated with syndrome(parent)
Hereditary disorder of endocrine system(parent)
Congenital atrophy of optic nerve(parent)
Disorder of ear(parent)
Congenital hearing disorder(parent)
Central nervous system complication(parent)
Hereditary hearing loss(parent)
Quick Facts
- SNOMED CT
- 734022008
- UMLS CUI
- C4518338
- Fully Specified Name
- Wolfram-like syndrome (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 22
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.