Overview
Wolman's disease is a disorder.
Auto-generated from clinical reference data. Not a substitute for medical advice.
Signs & Symptoms
Based on Human Phenotype Ontology (HPO) disease-phenotype annotations.
Acute liver failure
Always present (100%)HP:0006554
Poor weight gain
Always present (100%)HP:0001508
Reduced lysosomal acid lipase activity
Always present (100%)HP:0031205
Vomiting
Always present (100%)HP:0002013
Abdominal swelling
Very frequent (80-99%)HP:0003270
Adrenal calcification
Very frequent (80-99%)HP:0010512
Cognitive delay
Very frequent (80-99%)HP:0001263
Enlarged liver
Very frequent (80-99%)HP:0002240
Fat in feces
Very frequent (80-99%)HP:0002570
Hepatic insufficiency
Very frequent (80-99%)HP:0001399
Nausea and vomiting
Very frequent (80-99%)HP:0002017
Ascites
Frequent (30-79%)HP:0001541
Cachexia
Frequent (30-79%)HP:0004326
Large spleen
Frequent (30-79%)HP:0001744
Low number of red blood cells or haemoglobin
Frequent (30-79%)HP:0001903
Malnutrition
Frequent (30-79%)HP:0004395
Retarded growth
Frequent (30-79%)HP:0001510
Esophageal varix
Occasional (5-29%)HP:0002040
Hypoadrenalism
Occasional (5-29%)HP:0000846
Large vacuolated foam cells ('NP cells') on bone marrow biopsy
Occasional (5-29%)HP:0004333
Pyrexia
Occasional (5-29%)HP:0001945
Related Conditions
Quick Facts
- SNOMED CT
- 82500001
- UMLS CUI
- C0043208
- Fully Specified Name
- Wolman's disease (disorder)
- Specialists
- 0
- Diagnostic Biomarkers
- 0
- HPO Phenotypes
- 21
Medical Disclaimer
This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.
Clinical content is derived from the SNOMED CT clinical ontology and curated medical knowledge graphs.