Substance / Medication

Alemtuzumab

Overview

Active Ingredient
alemtuzumab
RxNorm CUI
117055

Indications

CAMPATH is indicated as a single agent for the treatment of B-cell chronic lymphocytic leukemia (B-CLL).

Labeler: Genzyme CorporationUpdated: 2025-11-05T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

None.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

13 trials linked to this intervention

13
Total Trials
2
Recruiting
7
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Alemtuzumab and thrombotic thrombocytopenic purpura: Analysis of an international surveillance database and systematic literature review.
Jacobs Jeremy W, Binns Thomas C, Schlafer Danielle et al. · Transfus Apher Sci · 2025
PMID: 39883995Meta-AnalysisFull text (PMC)
Risk of secondary autoimmune diseases with alemtuzumab treatment for multiple sclerosis: a systematic review and meta-analysis.
Yang Jianguo, Sun Yuying, Zhou Xinpeng et al. · Front Immunol · 2024
PMID: 38690271Meta-AnalysisFull text (PMC)
The role of alemtuzumab in the development of secondary autoimmunity in multiple Sclerosis: a systematic review.
Jimenez-Sanchez Sofia, Maksoud Rebekah, Eaton-Fitch Natalie et al. · J Neuroinflammation · 2024
PMID: 39487492Meta-AnalysisFull text (PMC)
Update on infective complications in patients treated with alemtuzumab for multiple sclerosis: review and meta-analysis of real-world and randomized studies.
Buonomo Antonio Riccardo, Viceconte Giulio, Zappulo Emanuela et al. · Expert Opin Drug Saf · 2021
PMID: 34310251Meta-Analysis
Alemtuzumab-induced thyroid events in multiple sclerosis: a systematic review and meta-analysis.
Scappaticcio L, Castellana M, Virili C et al. · J Endocrinol Invest · 2020
PMID: 31452116Meta-Analysis
Alemtuzumab versus interferon beta 1a for relapsing-remitting multiple sclerosis.
Zhang Jian, Shi Shengliang, Zhang Yueling et al. · Cochrane Database Syst Rev · 2017
PMID: 29178444Meta-AnalysisFull text (PMC)
Alemtuzumab for multiple sclerosis.
Riera Rachel, Porfírio Gustavo J M, Torloni Maria R · Cochrane Database Syst Rev · 2016
PMID: 27082500Meta-AnalysisFull text (PMC)
Alemtuzumab: a new therapy for active relapsing-remitting multiple sclerosis.
Hartung Hans-Peter, Aktas Orhan, Boyko Alexey N · Mult Scler · 2015
PMID: 25344374Meta-AnalysisFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Alemtuzumab (substance)
SNOMED CT
129472003
UMLS CUI
C0383429
RxNorm CUI
117055
Labeler
Genzyme Corporation

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
13
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.