Substance / Medication

Ammonium lactate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Ichthyosis vulgaris

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

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A randomized, double-blind, placebo-controlled study to evaluate the efficacy in AD of liquid soap containing 12% ammonium lactate + 20% urea.

Amichai B, Grunwald M H · Clin Exp Dermatol · 2009

PMID: 19486056RCT

Reduced burning and stinging associated with topical application of lactic acid 10% with strontium versus ammonium lactate 12%.

Haddican Madelaine, Gagliotti Matthew, Lebwohl Mark · Cutis · 2013

PMID: 23772434Observational

Increased Airport Scrutiny by the Transportation Security Administration of a Patient-Passenger Carrying Ammonium Lactate-Containing Moisturizer.

Zarbo Allison, Ouerfelli Ouathek, Klang Mark et al. · JAMA Dermatol · 2016

PMID: 27486908Case Report

[Unilateral nevus comedonicus: efficacy after treatment with 12% ammonium lactate].

Bordel María Teresa, Miranda Alberto · Actas Dermosifiliogr · 2006

PMID: 16595123Case Report

Topical therapy with tretinoin and ammonium lactate for acanthosis nigricans associated with obesity.

Blobstein Steven H · Cutis · 2003

PMID: 12553628Case Report

Axillary intertriginous granular parakeratosis responsive to topical calcipotriene and ammonium lactate.

Contreras Michael E, Gottfried Lisa C, Bang Ran H et al. · Int J Dermatol · 2003

PMID: 12755978Case Report

Phase change composite based on protic ionic liquids 2-hydroxyethylammonium lactate and stearic acid for thermal energy storage systems at intermediate temperatures.

Mokhtarpour Masumeh, Shekaari Hemayat, Rostami Ali et al. · Sci Rep · 2025

PMID: 40624029OtherFull text (PMC)

Evaluation of Radiation and Ammonium Lactate Effects on Hyaluronic Acid Expression as a Pro-cancerous Factor in Supernatant and Exosome Isolated from Supernatant of Primary Mouse Fibroblast Cell Culture.

Zare Nasrin, Kefayat Amirhosein, Javanmard Shaghayegh Haghjooy · Int J Prev Med · 2020

PMID: 33088453OtherFull text (PMC)

Comparison of long-pulsed alexandrite laser and topical tretinoin-ammonium lactate in axillary acanthosis nigricans: A case series of patients in a before-after trial.

Ehsani Amirhoushang, Noormohammadpour Pedram, Goodarzi Azadeh et al. · Caspian J Intern Med · 2016

PMID: 27999648OtherFull text (PMC)

Investigation of ammonium lactate supplementation on fermentation end products and bacterial assimilation of nitrogen in dual-flow continuous culture.

Wagner B K, Wenner B A, Plank J E et al. · J Dairy Sci · 2018

PMID: 30126597Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Ammonium lactate (substance)
SNOMED CT: 409385009
UMLS CUI: C0718495

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.