Substance / Medication

Amoxicillin

Overview

Active Ingredient
amoxicillin
RxNorm CUI
723

Indications

Adults and Pediatric Patients Adult Patients only Helicobacter pylori (H. pylori) Triple therapy forwith clarithromycin and lansoprazole: H. pylori H. pylori H. pylori Amoxicillin, in combination with clarithromycin plus lansoprazole as triple therapy, is indicated for the treatment of patients withinfection and duodenal ulcer disease (active or 1-year history of a duodenal ulcer) to eradicate. Eradication ofhas been shown to reduce the risk of duodenal ulcer recurrence. H. pylori Dual therapy f

Labeler: Chartwell RX, LLCUpdated: 2025-12-22T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

Amoxicillin is contraindicated in patients who have experienced a serious hypersensitivity reaction (e.g., anaphylaxis or Stevens-Johnson syndrome) to amoxicillin or to other β-lactam antibacterial drugs (e.g., penicillins and cephalosporins).

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

5 trials linked to this intervention

5
Total Trials
2
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
The role of oral amoxicillin/clavulanic acid in the treatment of osteomyelitis: a systematic review.
Ercolin Elena Sofia Giovanna, Bäthis Holger, Marche Benedikt et al. · Eur J Trauma Emerg Surg · 2026
PMID: 41569452Meta-AnalysisFull text (PMC)
Helicobacter pylori eradication with high-dose proton pump inhibitor-amoxicillin dual therapy: A systematic review and meta-analysis.
Yeh Jia-Ai, Huang Huei-Kai, Chou Ai-Li et al. · Int J Antimicrob Agents · 2024
PMID: 38554984Meta-Analysis
Efficacy and safety of vonoprazan and high-dose amoxicillin dual therapy in eradicating Helicobacter pylori: A systematic review and meta-analysis.
Zhang Ju, Zhang Huan, Zhu Xiao-Jing et al. · Int J Antimicrob Agents · 2024
PMID: 39251094Meta-Analysis
Relationship Between Amoxicillin Use in Pregnancy and Congenital Anomalies: A Systematic Review.
Bahri Narjes, Dashti Sareh, Mohammadzadeh Alireza et al. · Curr Drug Res Rev · 2023
PMID: 36515039Meta-Analysis
Amoxicillin-associated Stevens-Johnson syndrome or toxic epidermal necrolysis: systematic review.
Pejcic Ana V, Milosavljevic Milos N, Folic Marko et al. · J Chemother · 2023
PMID: 35285784Meta-Analysis
A systematic review on photo-Fenton process as an efficient advanced oxidation for degradation of amoxicillin in aqueous environments.
Pirsaheb Meghdad, Hossaini Hiwa, Raad Nazanin Kiani et al. · Rev Environ Health · 2023
PMID: 35436046Meta-Analysis
Efficacy of antimicrobials or placebo compared to amoxicillin-clavulanate in children with acute otitis media: a systematic review.
Tsergouli Katerina, Karampatakis Nikolaos, Karampatakis Theodoros · Turk J Pediatr · 2023
PMID: 37395955Meta-Analysis

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Amoxicillin (substance)
SNOMED CT
372687004
UMLS CUI
C0002645
RxNorm CUI
723
Labeler
Chartwell RX, LLC

Clinical Data

This intervention maps to 13 entities in the Healos knowledge graph.

13
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
5
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.