Substance / Medication

Amphotericin B lipid complex

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
Drug-induced nephrotoxicity caused by amphotericin B lipid complex and liposomal amphotericin B: a review and meta-analysis.
Safdar Amar, Ma Jonathan, Saliba Fouzi et al. · Medicine (Baltimore) · 2010
PMID: 20616663Meta-Analysis
Micafungin versus amphotericin B lipid complex for the prevention of invasive fungal infections in high-risk liver transplant recipients.
Sun Hsin-Yun, Cacciarelli Thomas V, Singh Nina · Transplantation · 2013
PMID: 23842191Observational
Comparison of posaconazole versus weekly amphotericin B lipid complex for the prevention of invasive fungal infections in hematopoietic stem-cell transplantation.
Chaftari Anne-Marie, Hachem Ray Y, Ramos Elizabeth et al. · Transplantation · 2012
PMID: 22814329Observational
Comparative pharmacodynamics of amphotericin B lipid complex and liposomal amphotericin B in a murine model of pulmonary mucormycosis.
Lewis Russell E, Albert Nathan D, Liao Guangling et al. · Antimicrob Agents Chemother · 2010
PMID: 20038620ObservationalFull text (PMC)
The current role of amphotericin B lipid complex in managing systemic fungal infections.
Chu Patrick, Sadullah Shalal · Curr Med Res Opin · 2009
PMID: 19849324Observational
Efficacy of amphotericin B lipid complex in a rabbit model of coccidioidal meningitis.
Capilla Javier, Clemons Karl V, Sobel Raymond A et al. · J Antimicrob Chemother · 2007
PMID: 17646202Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Amphotericin B lipid complex (substance)
SNOMED CT
425953004
UMLS CUI
C4521099

Clinical Data

This intervention maps to 4 entities in the Healos knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.