Substance / Medication

Apalutamide

Overview

Active Ingredient
apalutamide
RxNorm CUI
1999574

Indications

ERLEADA is indicated for the treatment of patients with Metastatic castration-sensitive prostate cancer (mCSPC) Non-metastatic castration-resistant prostate cancer (nmCRPC)

Labeler: Janssen Products, LPUpdated: 2025-09-09T00:00:00.000ZFull label on DailyMed

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

Clinical Trials

1 trials linked to this intervention

1
Total Trials
1
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Apalutamide, enzalutamide, and darolutamide for non-metastatic castration-resistant prostate cancer: a systematic review and network meta-analysis.
Mori Keiichiro, Mostafaei Hadi, Pradere Benjamin et al. · Int J Clin Oncol · 2020
PMID: 32924096Meta-AnalysisFull text (PMC)
Bioequivalence and Food Effect Assessment of Apalutamide Tablets Relative to Erleada in Healthy Chinese Male Participants.
Li Ning, Wang Xuanxuan, Li Rui et al. · Clin Pharmacol Drug Dev · 2026
PMID: 40862641RCT
Apalutamide in Patients with High Burden of Metastatic Hormone-sensitive Prostate Cancer: A Subgroup Analysis of TITAN.
Rodriguez-Vida Alejo, Borque Angel, Lopez-Campos Fernando et al. · Eur Urol Oncol · 2025
PMID: 41027802RCT
Bioequivalence of 240 mg Apalutamide Tablets and Preparation in Aqueous Food Vehicles for Alternative Administration.
Yu Alex, Van Uffel Mieke, Jiao Juhui J et al. · Clin Pharmacol Drug Dev · 2024
PMID: 37987029RCT
Clinical characteristics associated with falls in patients with non-metastatic castration-resistant prostate cancer treated with apalutamide.
Pollock YaoYao, Smith Matthew R, Saad Fred et al. · Prostate Cancer Prostatic Dis · 2023
PMID: 36209239RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Health Goals

Goals connected through associated conditions

Quick Facts

Type
Substance / Medication
Fully Specified Name
Apalutamide (substance)
SNOMED CT
766972001
UMLS CUI
C4329353
RxNorm CUI
1999574
Labeler
Janssen Products, LP

Clinical Data

This intervention maps to 5 entities in the Healos knowledge graph.

1
Conditions
1
Biomarkers
2
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.