Substance / Medication

Apraclonidine

Overview

Active Ingredient
apraclonidine
RxNorm CUI
14845

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
TOPICAL APRACLONIDINE REDUCES PAIN AFTER INTRAVITREAL INJECTIONS: A Double-Blind Randomized Controlled Trial.
Lagstein Oded, Ben-Artzi Noa, Achiron Asaf et al. · Retina · 2017
PMID: 27841849RCT
Pupillometry study of brimonidine tartrate 0.2% and apraclonidine 0.5%.
Besada Eulogio, Reed Kimberly, Najman Perla et al. · J Clin Pharmacol · 2011
PMID: 21406599RCT
Apraclonidine and LASIK.
Aslanides Ioannis M, Tsiklis Nikolaos S, Pallikaris Ioannis G et al. · Ophthalmology · 2005
PMID: 16325717RCT
Effect of Apraclonidine and Diclofenac on Early Changes in Intraocular Pressure After Selective Laser Trabeculoplasty.
Thrane Vinita Rangroo, Thrane Alexander S, Bergo Cecilie et al. · J Glaucoma · 2020
PMID: 32053556Observational
Brinzolamide 1% versus apraclonidine 0.5% to prevent intraocular pressure elevation after neodymium:YAG laser posterior capsulotomy.
Unal Mustafa, Yücel Iclal, Akar Yusuf · J Cataract Refract Surg · 2006
PMID: 16931262Observational
Comparative efficacy of acetazolamide and apraclonidine in the control of intraocular pressure following phacoemulsification.
Scuderi Gianluca, Regine Federico, Perdicchi Andrea et al. · Ophthalmologica · 2006
PMID: 17095879Observational
Topical apraclonidine testing discloses pupillary sympathetic denervation in diabetic patients.
Koc Feray, Kansu Tulay, Kavuncu Sevim et al. · J Neuroophthalmol · 2006
PMID: 16518162Observational
Comparing efficacies of 0.5% apraclonidine with 4% cocaine in the diagnosis of horner syndrome in pediatric patients.
Chen Po-Liang, Chen Jiann-Torng, Lu Da-Wen et al. · J Ocul Pharmacol Ther · 2006
PMID: 16808679Observational
Clonidine provides an allergy-free alternative in glaucoma patients with proven allergy to apraclonidine.
Geyer O, Schmidt K G, Pianka P et al. · Graefes Arch Clin Exp Ophthalmol · 2000
PMID: 10766284Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Apraclonidine (substance)
SNOMED CT
391786008
UMLS CUI
C0048038
RxNorm CUI
14845

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.