Substance / Medication

Azelaic acid

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

10 trials linked to this intervention

10
Total Trials
0
Recruiting
6
With Results

Research Evidence

Published studies and systematic reviews

Sort:
A systematic review to evaluate the efficacy of azelaic acid in the management of acne, rosacea, melasma and skin aging.
King Sarah, Campbell Jo, Rowe Rebecca et al. · J Cosmet Dermatol · 2023
PMID: 37550898Meta-Analysis
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.
Liu Haibo, Yu Haiyan, Xia Jun et al. · Cochrane Database Syst Rev · 2020
PMID: 32356369Meta-AnalysisFull text (PMC)
Azelaic acid in the treatment of papulopustular rosacea: a systematic review of randomized controlled trials.
Liu Rosemarie H, Smith Molly K, Basta Sameh A et al. · Arch Dermatol · 2006
PMID: 16924055Meta-Analysis
Clinical and dermoscopic evaluation of combined (salicylic acid 20% and azelaic acid 20%) versus trichloroacetic acid 25% chemical peel in acne: an RCT.
Abdel Hay Rania, Hegazy Rehab, Abdel Hady Mohamed et al. · J Dermatolog Treat · 2019
PMID: 29862871RCT
Combination of glycolic acid peel and topical 20% azelaic acid cream in melasma patients: efficacy and improvement in quality of life.
Dayal Surabhi, Sahu Priyadarshini, Dua Ruchika · J Cosmet Dermatol · 2017
PMID: 27500896RCT
Efficacy of 15% azelaic acid in psoriasis vulgaris: a randomized, controlled clinical trial.
Iraji Fariba, Faghihi Gita, Siadat Amir Hossein et al. · J Drugs Dermatol · 2010
PMID: 20684146RCT
Cumulative irritation potential among metronidazole gel 1%, metronidazole gel 0.75%, and azelaic acid gel 15%.
Colón Luz E, Johnson Lori A, Gottschalk Ronald W · Cutis · 2007
PMID: 17500380RCT

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Azelaic acid (substance)
SNOMED CT
386936005
UMLS CUI
C0052761

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
10
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.