Substance / Medication

Azelastine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Research Evidence

Published studies and systematic reviews

Sort:
The efficiency of azelastine hydrochloride and fluticasone propionate nasal spray to improve PAP adherence in patients with obstructive sleep apnea.
Wongchan Rachata, Tepwimonpetkun Chatkarin, Kitsongsermthon Jutarat et al. · Sci Rep · 2025
PMID: 40287492RCTFull text (PMC)
Determination of the Bioavailability of 3 Intranasal Formulations of Azelastine Hydrochloride in Healthy Male Volunteers.
Bousquet Jean, Klimek Ludger, Liu Mark et al. · Clin Pharmacol Drug Dev · 2025
PMID: 39789734RCT
Onset of efficacy of azelastine hydrochloride 0.15% nasal spray for allergic rhinitis in an environmental exposure chamber.
Hsu Shu-Ning, Sajjad Fatima, Brigham Elizabeth et al. · Ann Allergy Asthma Immunol · 2024
PMID: 39067509RCT
Azelastine hydrochloride on behavioral and psychological symptoms and activities of daily living in dementia patients.
Hatakeyama Aiko, Fujii Masahiko, Hatakeyama Reiko et al. · Geriatr Gerontol Int · 2008
PMID: 18713191RCT
A clinical pharmacokinetic study comparing two azelastine hydrochloride nasal formulations in a single-dose design.
Du Daniel, Targett Darren, Stolberg Erhard et al. · Eur J Drug Metab Pharmacokinet · 2014
PMID: 23681835Observational
Combination therapy with azelastine hydrochloride nasal spray and fluticasone propionate nasal spray in the treatment of patients with seasonal allergic rhinitis.
Ratner Paul H, Hampel Frank, Van Bavel Julius et al. · Ann Allergy Asthma Immunol · 2008
PMID: 18254486Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Azelastine hydrochloride (substance)
SNOMED CT
108646003
UMLS CUI
C0771004

Clinical Data

This intervention maps to 4 entities in the Healos knowledge graph.

4
Conditions
0
Biomarkers
0
Specialists
0
Symptoms

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.