Substance / Medication

Bendamustine hydrochloride

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

2 trials linked to this intervention

2
Total Trials
1
Recruiting
1
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Oral formulation of bendamustine hydrochloride for patients with advanced solid tumors; a phase 1 study.
Shimizu Toshio, Nakagawa Kazuhiko, Hayashi Hidetoshi et al. · Invest New Drugs · 2023
PMID: 36331674ObservationalFull text (PMC)
Two cases of malignant lymphoma with reactivation of resolved hepatitis B virus infection after bendamustine hydrochloride monotherapy.
Hiraki Yoshiki, Kawano Akira, Shigematsu Hirohisa et al. · Nihon Shokakibyo Gakkai Zasshi · 2016
PMID: 27593368Case Report
Chemoimmunotherapy with bendamustine hydrochloride and alemtuzumab demonstrates synergism in T-prolymphocytic leukemia.
Yong Hao Xiang, Linn Yeh Ching, Ong Kiat Hoe et al. · Leuk Res · 2012
PMID: 22613190Case Report
Bendamustine hydrochloride in patients with B-cell malignancies who have comorbidities - is there an optimal dose?
Gordon Max J, Lewis Lionel D, Brown Jennifer R et al. · Expert Rev Hematol · 2017
PMID: 28664772Review
Polymorphic forms of bendamustine hydrochloride: crystal structure, thermal properties and stability at ambient conditions.
Gaztañaga Pablo, Baggio Ricardo, Vega Daniel Roberto · Acta Crystallogr B Struct Sci Cryst Eng Mater · 2019
PMID: 32830673Other
An efficient and facile synthesis of deuterium-labeled anticancer agent bendamustine hydrochloride.
Liu Baomin, Qin Hui, Zhang Yinsheng · J Labelled Comp Radiopharm · 2018
PMID: 29770488Other
Nanosized complexation assemblies housed inside reverse micelles churn out monocytic delivery cores for bendamustine hydrochloride.
Singh Yuvraj, Chandrashekhar Anumandla, Meher Jaya Gopal et al. · Eur J Pharm Biopharm · 2017
PMID: 28088632Other
Novel Validated RP-HPLC Method for Bendamustine Hydrochloride Based on Ion-pair Chromatography: Application in Determining Infusion Stability and Pharmacokinetics.
Singh Yuvraj, Chandrashekar Anumandla, Pawar Vivek K et al. · J Chromatogr Sci · 2017
PMID: 27993861Preclinical

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Bendamustine hydrochloride (substance)
SNOMED CT
430082006
UMLS CUI
C0772139

Clinical Data

This intervention maps to 2 entities in the Healos knowledge graph.

2
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
2
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.