Substance / Medication

Besifloxacin

Overview

Active Ingredient
besifloxacin
RxNorm CUI
819911

Indications

Besifloxacin ophthalmic suspension 0.6% is indicated for the treatment of bacterial conjunctivitis caused by susceptible isolates of the following bacteria: Streptococcus salivarius * Aerococcus viridans * CDC coryneform group G Corynebacterium pseudodiphtheriticum* Corynebacterium striatum* Haemophilus influenzae Moraxella catarrhalis* Moraxella lacunata* Pseudomonas aeruginosa* Staphylococcus aureus Staphylococcus epidermidis Staphylococcus hominis* Staphylococcus lugdunensis* Staphylococcus w

Labeler: Bausch & Lomb Americas Inc.Updated: 2026-01-12T00:00:00.000ZFull label on DailyMed

Contraindications

When this intervention should not be used

None.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Detailed dosage and administration information is available in the full FDA drug label.

View full prescribing information on DailyMed

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

4 trials linked to this intervention

4
Total Trials
0
Recruiting
3
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Besifloxacin ophthalmic suspension 0.6% in the treatment of bacterial keratitis: a retrospective safety surveillance study.
Schechter Barry A, Parekh Jai G, Trattler William · J Ocul Pharmacol Ther · 2015
PMID: 25409447Observational
Safety of besifloxacin ophthalmic suspension 0.6% in cataract and LASIK surgery patients.
Majmudar Parag A, Clinch Thomas E · Cornea · 2014
PMID: 24637269ObservationalFull text (PMC)
Comparative in vitro susceptibility of besifloxacin and seven comparators against ciprofloxacin- and methicillin-susceptible/nonsusceptible staphylococci.
Miller Darlene, Chang Jonathan S, Flynn Harry W et al. · J Ocul Pharmacol Ther · 2013
PMID: 23289847Observational
The safety of besifloxacin ophthalmic suspension 0.6 % used three times daily for 7 days in the treatment of bacterial conjunctivitis.
Malhotra Ranjan, Ackerman Stacey, Gearinger Lynne S et al. · Drugs R D · 2013
PMID: 24142473ObservationalFull text (PMC)
Safety of besifloxacin ophthalmic suspension 0.6% in cataract surgery patients.
Parekh Jai G, Newsom T Hunter, Nielsen Steven · J Cataract Refract Surg · 2012
PMID: 22999608Observational
Besifloxacin ophthalmic suspension 0.6% administered twice daily for 3 days in the treatment of bacterial conjunctivitis in adults and children.
DeLeon Jesse, Silverstein Bruce E, Allaire Catherine et al. · Clin Drug Investig · 2012
PMID: 22420526Observational
Human aqueous humor concentrations of besifloxacin, moxifloxacin, and gatifloxacin after topical ocular application.
Donnenfeld Eric D, Comstock Timothy L, Proksch Joel W · J Cataract Refract Surg · 2011
PMID: 21596251Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Adverse reaction and safety data for this drug is sourced from the FDA-approved label.

View adverse reactions & drug interactions on DailyMed

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Besifloxacin (substance)
SNOMED CT
442870007
UMLS CUI
C2351042
RxNorm CUI
819911
Labeler
Bausch & Lomb Americas Inc.

Clinical Data

This intervention maps to 6 entities in the Healos knowledge graph.

6
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
4
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.