Substance / Medication

Bosutinib

Overview

Active Ingredient
bosutinib
RxNorm CUI
1307619

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

No related conditions have been mapped yet. Condition-intervention linkages are derived from SNOMED CT relationships and will expand as the knowledge graph grows.

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

1 trials linked to this intervention

1
Total Trials
1
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
Pharmacokinetic-pharmacodynamic relationship of bosutinib in patients with chronic phase chronic myeloid leukemia.
Hsyu Poe-Hirr, Mould Diane R, Upton Richard N et al. · Cancer Chemother Pharmacol · 2013
PMID: 23070145Meta-Analysis
Evaluation of the pharmacokinetics and safety of bosutinib in patients with chronic hepatic impairment and matched healthy subjects.
Abbas Richat, Chalon Stephan, Leister Cathie et al. · Cancer Chemother Pharmacol · 2013
PMID: 23053269RCT
Effect of ketoconazole on the pharmacokinetics of oral bosutinib in healthy subjects.
Abbas Richat, Hug Bruce A, Leister Cathie et al. · J Clin Pharmacol · 2011
PMID: 21148045RCT
Bosutinib Treatment of Chronic Myeloid Leukemia in Lombardy.
Iurlo Alessandra, Bucelli Cristina, Intermesoli Tamara et al. · Acta Haematol · 2025
PMID: 39293408Observational
Bosutinib versus imatinib for newly diagnosed chronic phase chronic myeloid leukemia: final results from the BFORE trial.
Brümmendorf Tim H, Cortes Jorge E, Milojkovic Dragana et al. · Leukemia · 2022
PMID: 35643868ObservationalFull text (PMC)

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Bosutinib (substance)
SNOMED CT
703128001
UMLS CUI
C1831731
RxNorm CUI
1307619

Clinical Data

This intervention maps to 0 entities in the Healos knowledge graph.

0
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.