Substance / Medication

Cetrorelix

SNOMED 395906005 UMLS C0209366

Overview

Active Ingredient

cetrorelix

RxNorm CUI

68147

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Secondary Meig's syndrome

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

17 trials linked to this intervention

Total Trials

Recruiting

With Results

Recent Trials

NATural Ovarian Stimulation

NCT02892942Phase 4Completed129 enrolled

Sex Differences in Myocardial Steatosis Induced Left Ventricular Dysfunction

NCT04671966Phase 4Recruiting100 enrolled

Effect of GnRH Agonist vs GnRH Antagonist on Oocyte Morphology in Polycystic Ovary Syndrome Patients During IVF/ICSI

NCT04727684Phase 4Completed50 enrolled

Effect of GnRH Agonist vs GnRH Antagonist on IVF/ICSI Outcomes in Polycystic Ovary Syndrome Patients.

NCT04727671Phase 4Completed50 enrolled

Effect of GnRH Agonist vs GnRH Antagonist on IVF/ICSI Outcomes.

NCT04724343Phase 4Completed50 enrolled

View all 17 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Short-term treatment with a gonadotropin-releasing hormone antagonist, cetrorelix, in rheumatoid arthritis (AGRA): a randomized, double-blind, placebo-controlled study.

Kåss A S, Førre O T, Fagerland M W et al. · Scand J Rheumatol · 2014

PMID: 24182325RCTFull text (PMC)

Effects of cetrorelix, a GnRH-receptor antagonist, on gonadal axis in women with functional hypothalamic amenorrhea.

Berardelli Rita, Gianotti Laura, Karamouzis Ioannis et al. · Gynecol Endocrinol · 2011

PMID: 21204607RCT

Cetrorelix suppresses the preovulatory LH surge and ovulation induced by ovulation-inducing factor (OIF) present in llama seminal plasma.

Silva Mauricio E, Smulders Juan P, Guerra Monserrat et al. · Reprod Biol Endocrinol · 2011

PMID: 21624125RCTFull text (PMC)

Cetrorelix lowers premature luteinization rate in gonadotropin ovulation induction-intrauterine insemination cycles: a randomized-controlled clinical trial.

Steward Ryan G, Gill Inderbir, Williams Dan B et al. · Fertil Steril · 2011

PMID: 20810107RCT

Effect of cetrorelix dose on premature LH surge during ovarian stimulation.

Lin Y H, Seow K M, Chen H J et al. · Reprod Biomed Online · 2008

PMID: 18549685RCT

Reproductive outcome using a GnRH antagonist (cetrorelix) for luteolysis and follicular synchronization in poor responder IVF/ICSI patients treated with a flexible GnRH antagonist protocol.

Humaidan P, Bungum L, Bungum M et al. · Reprod Biomed Online · 2005

PMID: 16417730RCT

GnRH Antagonist Protocol With Cessation of Cetrorelix on Trigger Day Improves Embryological Outcomes for Patients With Sufficient Ovarian Reserve.

Xu Huihui, Zhao Shen, Gao Xinxing et al. · Front Endocrinol (Lausanne) · 2021

PMID: 34721305ObservationalFull text (PMC)

Is anti-Müllerian hormone a marker of acute cyclophosphamide-induced ovarian follicular destruction in mice pretreated with cetrorelix?

Browne Hyacinth N, Moon Kimberly S, Mumford Sunni L et al. · Fertil Steril · 2011

PMID: 21550044ObservationalFull text (PMC)

Randomized, comparative pilot study of pituitary suppression with depot leuprorelin versus cetrorelix acetate 3 mg in gonadotropin stimulation protocols for oocyte donors.

Martínez Fracisca, Clua Elisabeth, Santmartí Paula et al. · Fertil Steril · 2010

PMID: 20430379Observational

Safety and efficacy of mixing cetrorelix with follitropin alfa: a randomized study.

Lin Yu-Hung, Wen Yeong-Ray, Chang Yuanmay et al. · Fertil Steril · 2010

PMID: 19339001Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Cetrorelix (substance)
SNOMED CT: 395906005
UMLS CUI: C0209366
RxNorm CUI: 68147

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.