Substance / Medication

Cetrorelix acetate

Overview

Clinical overview including description, indications, and evidence base is pending physician authorship or FDA SPL integration. Graph-derived relationship data is available below.

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Secondary Meig's syndrome

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

7 trials linked to this intervention

Total Trials

Recruiting

With Results

Recent Trials

The Use of GnRH Agonist Trigger in the Prevention of OHSS

NCT00349258Phase 4Completed66 enrolled

Triggering of Final Oocyte Maturation With GnRHa (Buserelin) in GnRH Antagonist Cycles

NCT00627406Phase 4Completed384 enrolled

Short Versus Long Protocol for IVF and IVF+ICSI

NCT00756028Phase 4Completed1099 enrolled

Endometrial Receptivity After GnRH Agonist Triggering

NCT01500863Phase 4Completed35 enrolled

Co-administration of Low Dose hCG at the Time of GnRH Agonist Trigger or 35 Hours Later for the Prevention of OHSS

NCT01815138Phase 4Completed89 enrolled

View all 7 trials on ClinicalTrials.gov

Research Evidence

Published studies and systematic reviews

Sort:

Randomized, comparative pilot study of pituitary suppression with depot leuprorelin versus cetrorelix acetate 3 mg in gonadotropin stimulation protocols for oocyte donors.

Martínez Fracisca, Clua Elisabeth, Santmartí Paula et al. · Fertil Steril · 2010

PMID: 20430379Observational

Comparison of embryo implantation in Wistar rats that underwent ovarian stimulation using exogenous gonadotropins associated with cetrorelix acetate or leuprolide acetate.

Torres Mychelle de Medeiros Garcia, Donadio Nilson, Donadio Nilka Fernandes et al. · Fertil Steril · 2005

PMID: 16210016Observational

Effect of cetrorelix acetate on apoptosis and apoptosis regulatory factors in cultured uterine leiomyoma cells.

Kwon Ja-Young, Park Ki-Hyun, Park Young-Nyun et al. · Fertil Steril · 2005

PMID: 16275262Observational

Synthesis of Diastereomerically Pure Cetrorelix Acetate by Using Fmoc Solid-Phase Peptide Synthesis (SPPS) Strategy: A Commercially Viable Approach.

Aluri Kiran, Basavoju Srinivas, Rangisetty Jagadeesh B et al. · J Pept Sci · 2025

PMID: 40386934Other

Identification and structural elucidation of a new cetrorelix methylene dimer impurity in cetrorelix acetate by using LC-MS/MS.

Li Mingliang, Li Huapeng, Huang Heqing et al. · J Pharm Biomed Anal · 2021

PMID: 33611089Other

Efficacy and Safety of gonadotropin-releasing hormone (GnRH) Agonists Triptorelin Acetate and Cetrorelix Acetate in Assisted Reproduction.

Jiang Jingjing, Gao Shanshan, Xu Jin · Med Sci Monit · 2018

PMID: 30405094OtherFull text (PMC)

Development and Validation of a Reversed-phase HPLC Method for Assay of the Decapeptide Cetrorelix Acetate in Bulk and Pharmaceutical Dosage Forms.

Hooshfar Shirin, Mortazavi Seyed Alireza, Piryaei Mohammad et al. · Iran J Pharm Res · 2014

PMID: 24711828OtherFull text (PMC)

Gonadotropin-releasing hormone (GnRH) agonist leuprolide acetate and GnRH antagonist cetrorelix acetate directly inhibit leiomyoma extracellular matrix production.

Britten Joy Lynne, Malik Minnie, Levy Gary et al. · Fertil Steril · 2012

PMID: 22901846Other

Effect of a lower-dose cetrorelix acetate protocol on in-vitro fertilization outcome.

Tzeng Chii-Ruey, Chen Heng-Ju, Lin Yu-Hung et al. · Int J Gynaecol Obstet · 2008

PMID: 18045601Trial

Presurgical short term treatment of uterine fibroids with different doses of cetrorelix acetate: a double-blind, placebo-controlled multicenter study.

Engel Jörg B, Audebert Alain, Frydman René et al. · Eur J Obstet Gynecol Reprod Biol · 2007

PMID: 16930803Trial

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type: Substance / Medication
Fully Specified Name: Cetrorelix acetate (substance)
SNOMED CT: 412114000
UMLS CUI: C0872997

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

Conditions

Biomarkers

Specialists

Symptoms

Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.