Substance / Medication

Cevimeline

Overview

Active Ingredient
cevimeline
RxNorm CUI
44281

Indications & Related Conditions

Conditions associated via SNOMED clinical relationships

Administration & Protocol

Dosing, route, and treatment protocol

Administration details including route, dosing schedules, preparation instructions, and contraindications are pending physician authorship.

Monitoring & Follow-Up

Biomarkers relevant to this intervention via related conditions

No monitoring biomarkers have been mapped yet. Biomarker-intervention linkages are derived through related conditions and will expand as the knowledge graph grows.

Clinical Trials

1 trials linked to this intervention

1
Total Trials
0
Recruiting
0
With Results

Research Evidence

Published studies and systematic reviews

Sort:
[A study of the sialogogic effect of cevimeline gargle].
Yoshikawa Chizuko, Takamatsu Yasushi, Ogata Kentaro et al. · Gan To Kagaku Ryoho · 2013
PMID: 23411958RCT
Comparing the effectiveness and adverse effects of pilocarpine and cevimeline in patients with hyposalivation.
Farag Arwa M, Holliday Craig, Cimmino Joseph et al. · Oral Dis · 2019
PMID: 31520497Observational
Distinct effects of cevimeline and pilocarpine on salivary mechanisms, cardiovascular response and thirst sensation in rats.
Ono K, Inagaki T, Iida T et al. · Arch Oral Biol · 2012
PMID: 22099058Observational
Effectiveness of cevimeline to improve oral health in patients with postradiation xerostomia.
Witsell David L, Stinnett Sandra, Chambers Mark S · Head Neck · 2012
PMID: 22231734Observational
Dosage form design and in vitro/in vivo evaluation of cevimeline extended-release tablet formulations.
Tajiri Shinichiro, Kanamaru Taro, Kamada Makoto et al. · Int J Pharm · 2010
PMID: 19747964Observational
Comparison of the effects of pilocarpine and cevimeline on salivary flow.
Braga M A, Tarzia O, Bergamaschi C C et al. · Int J Dent Hyg · 2009
PMID: 19416095Observational
Open-label, long-term safety study of cevimeline in the treatment of postirradiation xerostomia.
Chambers Mark S, Jones Christopher Uwe, Biel Merrill A et al. · Int J Radiat Oncol Biol Phys · 2007
PMID: 17855005Observational

Research data from MEDLINE/PubMed

Benefits & Expected Outcomes

Benefits, expected outcomes, efficacy data, and NNT (Number Needed to Treat) are pending physician authorship and evidence review.

Risks & Side Effects

Risk profile, common and serious adverse effects, contraindications, and drug interactions are pending physician authorship.

Related Symptoms

Symptoms associated with conditions this intervention addresses

No related symptoms have been mapped yet. Symptom linkages are derived through associated conditions.

Alternatives & Comparisons

Alternative treatments, comparison data, and clinical decision support are pending physician authorship.

Medical Disclaimer

This information is for educational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult with a qualified healthcare provider regarding any medical condition or treatment plan.

Do not start, stop, or change any treatment without consulting your healthcare provider.

Quick Facts

Type
Substance / Medication
Fully Specified Name
Cevimeline (substance)
SNOMED CT
409284005
UMLS CUI
C0093437
RxNorm CUI
44281

Clinical Data

This intervention maps to 1 entities in the Healos knowledge graph.

1
Conditions
0
Biomarkers
0
Specialists
0
Symptoms
1
Clinical Trials

Data is sourced from SNOMED CT, UMLS, and the Healos clinical knowledge graph. Content sections marked as pending require physician authorship. Consult a healthcare provider before starting any treatment.